Evidence map›Paper›PMID 39909532›Full record

ArticleBMJ open2025

Association between parity and gravidity & hypertension and blood pressure: protocol for a systematic review and meta-analysis.

Nabilah Gulamhusein, Badal S B Pattar, Sandra M Dumanski, Tyrone G Harrison, Sonia Butalia, Magali Robert, Jane A Schulz, Sofia B Ahmed

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nabilah GulamhuseinCumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID http://orcid.org/0009-0008-6743-8935
Badal S B PattarCumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID http://orcid.org/0000-0001-7711-1591
Sandra M DumanskiCumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Tyrone G HarrisonCumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID http://orcid.org/0000-0003-1068-8673
Sonia ButaliaCumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Magali RobertCumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Jane A SchulzFaculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Sofia B AhmedCumming School of Medicine, University of Calgary, Calgary, Alberta, Canada sofia.ahmed@albertahealthservices.ca.ORCID http://orcid.org/0000-0003-3000-2229

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCardiovascular disease is the leading cause of death among women worldwide, and hypertension is one of the most prevalent and modifiable risk factors. Parity and gravidity, independent of pregnancy complications, have each been associated with hypertension, although results are conflicting. Therefore, we propose to estimate the association between parity and gravidity with hypertension and blood pressure in a systematic review of the literature. METHODS AND ANALYSIS: A systematic review will be conducted to estimate the association between parity and gravidity and hypertension and blood pressure. Electronic databases (Excerpta Medica Database, Ovid MEDLINE, Cochrane Central Register of Controlled Trials, Cumulative Index to Nursing and Allied Health Literature Plus and Web of Science) will be searched from inception to January 2025. Two investigators will independently screen identified abstracts and select observational cohort studies, case-control studies and randomised controlled trials examining parity or gravidity and hypertension or blood pressure. Extracted data will include study and population characteristics, comorbidities, parity, gravidity, incidence of hypertension and changes in blood pressure, study quality and risk of bias. If there are sufficient data, they will be summarised using random effects meta-analysis to estimate the pooled risk ratio or odds ratio of hypertension. Stratified and subgroup analyses will be used to explore potential sources of heterogeneity. PROSPERO REGISTRATION NUMBER: CRD42024560535.

Indexed as

Blood PressureGravidityHypertensionParityFemaleHumansMeta-Analysis as TopicPregnancyResearch DesignRisk FactorsSystematic Reviews as TopicBlood PressureHypertensionPregnancyPregnant Women

Identifiers

PMID39909532
PMCPMC11800290

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.