Evidence map›Paper›PMID 39909520›Full record

ArticleBMJ open2025

Cohort profile: Outcome Monitoring After Cardiac Surgery (OMACS) - a prospective UK cohort study of cardiac surgery patients at the Bristol Heart Institute.

Katherine Joyce, Rachel Maishman, Terrie Walker-Smith, Helena Smartt, Emma Hopkins, Penny Lambert, Gianni Angelini, Chris A Rogers, Barnaby Reeves, Rachel Brierley and 1 more

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Katherine JoyceBristol Trials Centre, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0002-5539-7178
Rachel MaishmanBristol Trials Centre, University of Bristol, Bristol, UK.
Terrie Walker-SmithBristol Trials Centre, University of Bristol, Bristol, UK.
Helena SmarttBristol Trials Centre, University of Bristol, Bristol, UK.
Emma HopkinsBristol Heart Institute, Bristol, UK.
Penny LambertBristol Heart Institute, Bristol, UK.
Gianni AngeliniBristol Heart Institute, Bristol, UK.ORCID http://orcid.org/0000-0002-1753-3730
Chris A RogersUniversity of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0002-9624-2615
Barnaby ReevesUniversity of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0002-5101-9487
Rachel BrierleyBristol Trials Centre, University of Bristol, Bristol, UK.
Lucy CullifordBristol Trials Centre, University of Bristol, Bristol, UK lucy.culliford@bristol.ac.uk.ORCID http://orcid.org/0000-0002-9255-6617

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe Outcome Monitoring After Cardiac Surgery (OMACS) cohort study was set-up with the aim of establishing a rich source of biological samples and health status data from patients who undergo cardiac surgery. The objectives were to use these data to inform the design of new clinical studies and to provide samples and data to answer research questions.

participantsRecruitment began on 23 May 2016 and ended 31 May 2022. Adult patients undergoing cardiac surgery at University Hospitals Bristol and Weston NHS Foundation Trust were screened and approached for consent. Participants could optionally consent to provide biological samples (urine, blood and waste tissue) in addition to data. A total of 4068 patients consented to participate in the study with 2027 consenting to donate samples. Participants were sent quality-of-life follow-up questionnaires at 3 and 12 months after surgery. The clinical data were collected from hospital records/databases. FINDINGS TO DATE: The OMACS population appears to be representative of the wider cardiac surgery population with similar preoperative demography to those reported on the UK surgery population. To date, eight studies have been carried out by research teams using data from a total of 1165 OMACS participants. Two Studies Within A Trial have been performed by the OMACS study team. The format of the study patient information leaflet was not significantly associated with an increased recruitment rate, and an alternative theory-informed cover letter included with the 12-month follow-up questionnaires was not associated with an increase in questionnaire completion. Additional exploratory research carried out within the OMACS study has been presented at international conferences. FUTURE PLANS: The OMACS study is now closed. The cohort's data and samples will be available to share with researchers, providing an opportunity to answer a variety of research questions (eg, evaluating predictors of adverse outcomes after cardiac surgery such as biomarkers, surgical methods and pre-existing conditions). The data and samples will be available for sharing in a linked anonymised format. TRIAL REGISTRATION NUMBER: ISRCTN90204321 (date assigned: 21 January 2015).

Indexed as

Cardiac Surgical ProceduresQuality of LifeAdultAgedFemaleHumansMaleMiddle AgedProspective StudiesSurveys and QuestionnairesUnited KingdomCardiac surgeryCardiothoracic surgeryObservational Study

Identifiers

PMID39909520
PMCPMC11800208

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.