Evidence map›Paper›PMID 39909158›Full record

ArticleVirus research2025

Pathogenicity of avian reovirus variant in the immune organs of broiler chicks.

Haiyang Yu, Yudong Zhu, Qiong Wu, Wanjun Zhao, You Wang, Dong Wang, Huaguang Lu, Youxiang Diao, Yijing Li, Yi Tang

Abstract read
In one paragraph

Article in Virus research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Haiyang YuCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China; Tianjin Ringpu Bio-Technology Co, Ltd., Tianjin, China. Electronic address: 18763897716@163.com.
Yudong ZhuCollege of Animal Science and Technology, Shandong Agricultural University, Taian, China. Electronic address: zhuyudongxin@163.com.
Qiong WuMount Taishan Shengliyuan Group Co, Ltd., Taian, China. Electronic address: 15905482337@163.com.
Wanjun ZhaoCollege of Animal Science and Technology, Shandong Agricultural University, Taian, China. Electronic address: 1369944124@qq.com.
You WangTianjin Ringpu Bio-Technology Co, Ltd., Tianjin, China. Electronic address: zyd19991209@163.com.
Dong WangTianjin Ringpu Bio-Technology Co, Ltd., Tianjin, China. Electronic address: zyd19991209@gmail.com.
Huaguang LuDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, 16802, USA. Electronic address: hxl15@psu.edu.
Youxiang DiaoCollege of Animal Science and Technology, Shandong Agricultural University, Taian, China. Electronic address: yxdiao@163.com.
Yijing LiCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China. Electronic address: yijingli@163.com.
Yi TangInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China. Electronic address: tangyi@caas.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the infection rate of avian reovirus (ARV) in chicks has been continuously increasing, seriously endangering the healthy development of China's chicken farming industry. However, the pathogenicity of this virus in immune organs has been less studied. In this study, an ARV strain (Chicken/XJ/China/2022/01/16) was isolated from arthritic broiler chicks in Xinjiang province and whole genome sequencing of the ARV strain was performed using next generation sequencing (NGS) technology, and sequence analysis showed that the strain was a type V variant of the ARV gene. In order to further understand the pathogenicity of this strain in terms of immune organs, we randomized 120 healthy 1-day-old broilers equally into 3 groups (oral, footpad inoculation and control), where 2 experimental groups were inoculated with 0.2 mL of ARV (TCID

Indexed as

Orthoreovirus, AvianPoultry DiseasesReoviridae InfectionsAnimalsBursa of FabriciusChickensChinaGenome, ViralHigh-Throughput Nucleotide SequencingPhylogenySpleenVirulenceAvian reovirusChickensImmune organsSuppressive infection

Identifiers

PMID39909158
PMCPMC11848764

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.