ArticleCell2025
Rhodoquinone carries electrons in the mammalian electron transport chain.
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In one paragraph
Article in Cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Aglycemia triggers alternative electron transport to sustain mesenchymal stem cell survival under anoxia.Redox biology · 2026Article
- The diversity of terminal electron acceptors across eukaryotes.Trends in biochemical sciences · 2026Review
- Iron-addicted colorectal cancers exploit heme-complex II axis to resist oxidative cell death.Cell metabolism · 2026Article
- Global distribution of isoprenoid quinones across Bacteria.mSystems · 2026Article
- A method to synthesize analytical rhodoquinone standards for quantitative analysis in tissue specimen.bioRxiv : the preprint server for biology · 2026Article
- Novel duck reovirus σC hijacks the mitochondrial COQ6-CoQ10 axis to drive NLRP3-dependent pyroptosis.PLoS pathogens · 2026Article
- Review
- Cell biology's fantastic voyage to Planet Earth.Nature methods · 2026Article
- Ectopic expression of cytosolic DHODH uncouples de novo pyrimidine biosynthesis from mitochondrial electron transport.Nature metabolism · 2026Article
- Basal foraminifer endures anoxia via aerotolerant anaerobic mitochondria and unconventional energy metabolism.The ISME journal · 2026Article
- Uridine-sensitized screening identifies demethoxy-coenzyme Q and NUDT5 as regulators of nucleotide synthesis.Nature metabolism · 2025Article
- Dissecting Bioelectrical Networks in Photosynthetic Membranes with Electrochemistry.Journal of the American Chemical Society · 2025Article
- Understanding the Metabolic Effects of Surgically Induced Renal Ischemia in Humans: A Temporal Approach.Metabolites · 2025Article
- Protocol to extract and measure ubiquinone and rhodoquinone in murine tissues.STAR protocols · 2025Article
- Xenotopic synthetic biology: Prospective tools for delaying aging and age-related diseases.Science advances · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
32 authors.
Jonathan ValerosProgram in Molecular Medicine, UMass Chan Medical School, Worcester, MA 01605, USA.
Madison JeromeProgram in Molecular Medicine, UMass Chan Medical School, Worcester, MA 01605, USA.
Tenzin TseyangProgram in Molecular Medicine, UMass Chan Medical School, Worcester, MA 01605, USA.
Paula VoProgram in Molecular Medicine, UMass Chan Medical School, Worcester, MA 01605, USA.
Thang DoProgram in Molecular Medicine, UMass Chan Medical School, Worcester, MA 01605, USA.
Diana Fajardo PalominoProgram in Molecular Medicine, UMass Chan Medical School, Worcester, MA 01605, USA; Morningside Graduate School of Biomedical Sciences, UMass Chan Medical School, Worcester, MA 01605, USA.
Nils GrotehansProgram in Molecular Medicine, UMass Chan Medical School, Worcester, MA 01605, USA.
Manisha KunalaProgram in Molecular Medicine, UMass Chan Medical School, Worcester, MA 01605, USA; Morningside Graduate School of Biomedical Sciences, UMass Chan Medical School, Worcester, MA 01605, USA.
Alexandra E JerrettProgram in Molecular Medicine, UMass Chan Medical School, Worcester, MA 01605, USA; Morningside Graduate School of Biomedical Sciences, UMass Chan Medical School, Worcester, MA 01605, USA.
Nicolai R HathiramaniProgram in Molecular Medicine, UMass Chan Medical School, Worcester, MA 01605, USA; Morningside Graduate School of Biomedical Sciences, UMass Chan Medical School, Worcester, MA 01605, USA; Diabetes Center of Excellence, UMass Chan Medical School, Worcester, MA 01605, USA.
Michael MirekuProgram in Molecular Medicine, UMass Chan Medical School, Worcester, MA 01605, USA.
Rayna Y MageshDepartment of Systems Biology, UMass Chan Medical School, Worcester, MA 01605, USA.
Batuhan YenilmezProgram in Molecular Medicine, UMass Chan Medical School, Worcester, MA 01605, USA.
Paul C RosenMassachusetts Institute of Technology, Cambridge, MA 02142, USA.
Jessica L MannMassachusetts Institute of Technology, Cambridge, MA 02142, USA.
Jacob W MyersProgram in Molecular Medicine, UMass Chan Medical School, Worcester, MA 01605, USA.
Tenzin KunchokWhitehead Institute, Cambridge, MA 02142, USA.
Tanner L ManningDepartment of Chemistry and Biochemistry, Gonzaga University, Spokane, WA 99258, USA.
Lily N BoerckerDepartment of Chemistry and Biochemistry, Gonzaga University, Spokane, WA 99258, USA.
Paige E CarrDepartment of Chemistry and Biochemistry, Gonzaga University, Spokane, WA 99258, USA.
Muhammad Bin MunimMassachusetts Institute of Technology, Cambridge, MA 02142, USA.
Caroline A LewisProgram in Molecular Medicine, UMass Chan Medical School, Worcester, MA 01605, USA.
David M SabatiniInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo n. 2, 166 10 Prague, Czech Republic; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Boston Branch, 840 Memorial Drive, Cambridge, MA 02139, USA.
Mark KellyProgram in Molecular Medicine, UMass Chan Medical School, Worcester, MA 01605, USA; Division of Cardiovascular Medicine, Department of Medicine, UMass Chan Medical School, Worcester, MA 01605, USA.
Jun XieHorae Gene Therapy Center, UMass Chan Medical School, Worcester, MA 01605, USA.
Michael P CzechProgram in Molecular Medicine, UMass Chan Medical School, Worcester, MA 01605, USA; Diabetes Center of Excellence, UMass Chan Medical School, Worcester, MA 01605, USA.
Guangping GaoHorae Gene Therapy Center, UMass Chan Medical School, Worcester, MA 01605, USA; Li Weibo Institute for Rare Disease Research, UMass Chan Medical School, Worcester, MA 01655, USA; Department of Microbiology and Physiological Systems, UMass Chan Medical School, Worcester, MA 01605, USA.
Jennifer N ShepherdDepartment of Chemistry and Biochemistry, Gonzaga University, Spokane, WA 99258, USA.
Amy K WalkerProgram in Molecular Medicine, UMass Chan Medical School, Worcester, MA 01605, USA.
Hahn KimSmall Molecule Screening Center, Princeton University, Princeton, NJ 08544, USA; Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.
Emma V WatsonDiabetes Center of Excellence, UMass Chan Medical School, Worcester, MA 01605, USA.
Jessica B SpinelliProgram in Molecular Medicine, UMass Chan Medical School, Worcester, MA 01605, USA. Electronic address: jessica.spinelli@umassmed.edu.
Funding
Role of methylation-dependent pathways in aging and stressR01AG053355 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Amy Karol Walker · 2017 to 2026
$4.5MCRISPR-enhanced adipocyte browning to improve glucose tolerance in obesity and diabetesR01DK130852 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MICHAEL P CZECH · 2021 to 2026
$3.4MDual transcriptional programs coordinate lipogenic and membrane stress responsive programs in C. elegans - SupplementR01AG068670 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI WALKER, AMY KAROL · 2021 to 2025
$2.1MUnderstanding Compartmentalized Leucine Metabolism Downstream of mTORC1 SignalingF31CA254162 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ROSEN, PAUL · 2020 to 2023
$186kNCI NIH HHS F31 CA254162NIA NIH HHS R01 AG053355NIA NIH HHS R01 AG068670NIDDK NIH HHS R01 DK130852
Abstract
Ubiquinone (UQ), the only known electron carrier in the mammalian electron transport chain (ETC), preferentially delivers electrons to the terminal electron acceptor oxygen (O
Indexed as
UbiquinoneAnimalsElectronsElectron TransportFumaratesHumansHypoxiaMiceMice, Inbred C57BLMitochondriaOxygenSuccinate DehydrogenaseFumaratesOxygenrhodoquinoneSuccinate DehydrogenaseUbiquinoneelectron transport chainhypoxiaischemiametabolismmitochondriarhodoquinone
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.