Evidence map›Paper›PMID 39908468›Full record

Observational studyNeurology2025

Association of Race and Ethnicity With Emergency Room Rate of Migraine Diagnosis, Testing, and Management in Children With Headache.

Danielle Kellier, Marissa Maliakal Anto, Matt Hall, Jennifer Marin, Kendall Nash, Elizabeth M Wells, Nicholas S Abend, Melissa L Hutchinson, Mahendranath Moharir, Ricka Denise Messer and 5 more

Abstract readComparative StudyObservational Study
In one paragraph

Observational study in Neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Danielle KellierPerelman School of Medicine at the University of Pennsylvania, Philadelphia.ORCID 0000-0001-7811-3468
Marissa Maliakal AntoPerelman School of Medicine at the University of Pennsylvania, Philadelphia.ORCID 0000-0001-5923-2285
Matt HallChildren's Hospital Association, Lenexa, KS.
Jennifer MarinDepartments of Pediatrics, Emergency Medicine, and Radiology, University of Pittsburgh School of Medicine, PA.
Kendall NashDivision of Child Neurology, Departments of Neurology and Pediatrics, University of California, San Francisco, Benioff Children's Hospital San Francisco.
Elizabeth M WellsCenter for Neuroscience and Behavioral Medicine, Children's National Hospital and the George Washington University School of Medicine and Health Sciences, DC.
Nicholas S AbendPerelman School of Medicine at the University of Pennsylvania, Philadelphia.ORCID 0000-0001-6166-2663
Melissa L HutchinsonNeurology Division, Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children's Hospital, Columbus.
Mahendranath MoharirDivision of Neurology, Department of Pediatrics, The Hospital for Sick Children and University of Toronto, Ontario, Canada.
Ricka Denise MesserSection of Child Neurology, Department of Pediatrics, University of Colorado, Aurora.
Jamie Lee PalaganasDivision of Child Neurology, Department of Pediatrics, Weill Cornell Medicine, New York Presbyterian Hospital, NY; and.
Juan PiantinoSection of Child Neurology, Department of Pediatrics, Oregon Health & Science University, Portland.
Christina SzperkaPerelman School of Medicine at the University of Pennsylvania, Philadelphia.ORCID 0000-0003-4786-8889
Craig PressPerelman School of Medicine at the University of Pennsylvania, Philadelphia.ORCID 0000-0003-4435-206X
as the Pediatric Neurohospitalist Work Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesHeadache evaluation and treatment are believed to be influenced by race and ethnicity. Specific headache diagnosis assigned in the pediatric emergency department (ED) may compound disparities. We sought to investigate racial and ethnic disparities in the diagnosis, testing, and treatment of pediatric patients with headache presenting to the ED.

methodsWe performed a cross-sectional analysis of ED visits from 49 children's hospitals between 2016 and 2022 from the Pediatric Health Information System, an administrative database of ED and hospitalized encounters within children's hospitals in the United States. Index encounters in the ED from patients (aged 5-21 years, median age 13 [10-15]) with a primary diagnosis of migraine, headache, new daily persistent headache, or tension-type headache were included. Encounters with trauma, infection, and malignancy where secondary headache was possible were excluded. The primary outcomes were the rates of migraine diagnosis, testing, and treatment. We used generalized estimating equations to estimate associations between race and ethnicity and outcomes after adjusting for demographic factors, medical complexity, visit timing, and final headache diagnosis.

resultsA total of 309,678 encounters were included while 61,677 repeat visits, 81,821 visits with diagnoses suggestive of secondary headache, and 5,714 visits from 3 hospitals with sparse data on patient race/ethnicity were excluded. Of 160,466 eligible visits (59.8% female), 41% were by non-Hispanic White (NHW) children, 24.8% non-Hispanic Black (NHB), and 26.0% Hispanic/Latino (HL). NHW children were more frequently diagnosed with migraine (45.5% vs NHB 28.2% and HL 28.3%, DISCUSSION: NHB and HL children in the pediatric ED with headache receive fewer migraine diagnoses, less testing, and less intensive treatment compared with NHW children. Beyond affecting headache management, this inequity in migraine diagnosis requires further consideration to include children from marginalized racial and ethnic groups in future migraine research.

Indexed as

Emergency Service, HospitalEthnicityHealthcare DisparitiesMigraine DisordersRacial GroupsAdolescentBlack or African AmericanChildChild, PreschoolCross-Sectional StudiesFemaleHispanic or LatinoHumansMaleUnited StatesWhite

Identifiers

PMID39908468
PMCPMC11795614

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.