ArticleScience advances2025
Trichome development of systemic developing leaves is regulated by a nutrient sensor-relay mechanism within mature leaves.
Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Hormone-metabolism crosstalk in plants: an integrated signaling network coordinating growth and stress adaptation.Plant signaling & behavior · 2026Review
- Article
- A comparative framework for trichome and trichome-derived epidermal appendage development across model glycophytes and halophytes.Plant cell reports · 2026Review
- Integrated transcriptomic and metabolomic analysis reveals the regulatory role of lignin biosynthesis in raspberry (Rubus niveus) prickle development.BMC plant biology · 2026Article
- Limited phosphate resources are efficiently allocated to each organ by the PHR1-EIN3/EIL1 module to coordinate their establishment.Science advances · 2025Article
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Authors and funding
8 authors.
Funding
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Abstract
Trichome initiation and development is regulated by a diverse range of environmental signals. However, how leaf carbohydrate status determines the trichome initiation and development of systemic developing leaves remains unclear. Here, we found that a specific organ (such as a mature leaf) could function as a nutrient sensor, subsequently promoting or suppressing nonautonomous regulation of trichome initiation and development in response to alternations in nutrient levels. This physical phenomenon was regulated by a sucrose ⟶ ACS7 ⟶ ethylene ⟶ EIN3 ⟶ SUC4 ⟶ sucrose pathway in mature leaves, with a remote control of trichome production in newly developing leaves via a sucrose ⟶ ACS7 ⟶ ethylene ⟶ EIN3 ⟶ TTG1 pathway. These data provide insights into how mature leaves function as nutrient sensors that control trichome formation within distant developing leaves through a nutrient sensor-relay mechanism. Our findings uncover both a previously unidentified, nutrient sensing-regulatory mechanism and the cognate underpinning molecular architecture.
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