Evidence map›Paper›PMID 39908350›Full record

ArticleScience translational medicine2025

Fuyi Liao, Dequan Zhou, Marlene Cano, Zhiyi Liu, Davide Scozzi, Laneshia K Tague, Derek E Byers, Wenjun Li, Jothilingam Sivapackiam, Vijay Sharma and 6 more

Abstract read
In one paragraph

Article in Science translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. International Society for Heart and Lung Transplantation Scientific Statement on pulmonary antibody-mediated rejection and proposed graft, antibody, and pathology (GAP) definition.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2026
    Guideline
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Tolerogenic lung allograft microenvironment suppresses pathogenic tissue remodeling following respiratory virus infection in mice.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article
  12. Emerging roles for complement in lung transplantation.The Journal of clinical investigation · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Fuyi LiaoDepartment of Surgery, Division of Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0001-7733-084X
Dequan ZhouDepartment of Surgery, Division of Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0009-0009-7288-9981
Marlene CanoDepartment of Medicine, Division of Pulmonology & Critical Care Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-2368-9256
Zhiyi LiuDepartment of Surgery, Division of Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0009-0008-9452-0547
Davide ScozziDepartment of Surgery, Division of Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-4049-1591
Laneshia K TagueDepartment of Medicine, Division of Pulmonology & Critical Care Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-6243-1901
Derek E ByersDepartment of Medicine, Division of Pulmonology & Critical Care Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0001-7371-9153
Wenjun LiDepartment of Surgery, Division of Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-1923-5016
Jothilingam SivapackiamMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0001-7979-1893
Vijay SharmaMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Alexander S KrupnickDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD 21201, USA.ORCID 0000-0002-1790-6197
Dara W FrankDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Daniel KreiselDepartment of Surgery, Division of Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-7711-8651
Hrishikesh S KulkarniDepartment of Medicine, Division of Pulmonology & Critical Care Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0003-4830-5084
Ramsey R HachemDepartment of Internal Medicine, Division of Respiratory, Critical Care, and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, UT 84108, USA.ORCID 0000-0002-0708-1937
Andrew E GelmanDepartment of Surgery, Division of Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-0711-6343

Funding

The Role of Neutrophils in Regulating Lung Transplant ToleranceP01AI116501 · NIAID · WASHINGTON UNIVERSITY · PI Wenjun Li · 2015 to 2026
$19.4M
Training/DisseminationP41EB025815 · NIBIB · WASHINGTON UNIVERSITY · PI Robert J. Gropler · 2018 to 2026
$12.7M
THE ROLE OF ISCHEMIA REPERFUSION INJURY IN LUNG ALLOGRAFT REJECTIONR01HL094601 · NHLBI · WASHINGTON UNIVERSITY · PI Andrew Eric Gelman, Daniel Kreisel · 2009 to 2026
$6.9M
The Role of Eosinophils in the Lung AllograftR01AI145108 · NIAID · UNIVERSITY OF VIRGINIA · PI Elizabeth A Jacobsen, ALEXANDER S. KRUPNICK · 2019 to 2026
$4.1M
POSITRON EMISSION TOMOGRAPHIC IMAGING OF LUNG TRANSPLANTR01HL121218 · NHLBI · WASHINGTON UNIVERSITY · PI CHEN, DELPHINE L, GELMAN, ANDREW ERIC · 2014 to 2017
$2.8M
PET Tracer for Imaging of Lung InflammationR01HL167277 · NHLBI · WASHINGTON UNIVERSITY · PI Andrew Eric Gelman, Vijay Sharma · 2023 to 2026
$2.7M
Lung epithelial cell-derived C3 in acute lung injuryR01HL169860 · NHLBI · WASHINGTON UNIVERSITY · PI Hrishikesh Satish Kulkarni · 2023 to 2026
$2.3M
Targeting a Defined Surgical Stress-Induced Inflammatory Pathway to Improve Peri-Operative OutcomesR01HL166402 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI Elizabeth A Jacobsen, ALEXANDER S. KRUPNICK · 2023 to 2026
$2.2M
Organ donor circadian clocks in transplantation acceptanceR01HL173976 · NHLBI · WASHINGTON UNIVERSITY · PI Andrew Eric Gelman, Jeffrey Adam Haspel · 2025 to 2026
$1.4M
C3 Mitigates Epithelial Injury in PneumoniaK08HL148510 · NHLBI · WASHINGTON UNIVERSITY · PI KULKARNI, HRISHIKESH SATISH · 2019 to 2023
$740k
Influence of Mycophenolic Acid Pharmacogenomics on Lung Transplant OutcomesK01HL155231 · NHLBI · WASHINGTON UNIVERSITY · PI TAGUE, LANESHIA K · 2021 to 2024
$596k
NHLBI NIH HHS K01 HL155231NHLBI NIH HHS K08 HL148510NHLBI NIH HHS R01 HL094601NHLBI NIH HHS R01 HL121218NHLBI NIH HHS R01 HL166402NHLBI NIH HHS R01 HL167277NHLBI NIH HHS R01 HL169860NHLBI NIH HHS R01 HL173976NIAID NIH HHS P01 AI116501NIAID NIH HHS R01 AI145108NIBIB NIH HHS P41 EB025815
6 · The paper itself

Abstract

How pathogens inhibit transplant tolerance remains unclear. Here, we found that

Indexed as

AntibodiesGraft RejectionLung TransplantationPseudomonas aeruginosaPseudomonas InfectionsAnimalsApoptosisCD4-Positive T-LymphocytesMiceMice, Inbred C57BLMyeloid Differentiation Factor 88Type III Secretion SystemsAntibodiesMyeloid Differentiation Factor 88Type III Secretion Systems

Identifiers

PMID39908350
PMCPMC12335241

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.