Evidence map›Paper›PMID 39908302›Full record

ArticlePloS one2025

Experimental assessment of damage and microplastic release during cyclic loading of clear aligners.

Claudia Barile, Claudia Cianci, Vimalathithan Paramsamy Kannan, Giovanni Pappalettera, Carmine Pappalettere, Caterina Casavola, Michele Laurenziello, Domenico Ciavarella

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Claudia BarileDipartimento di Meccanica, Matematica e Management, Politecnico di Bari, Bari, Italy.ORCID 0000-0002-8682-6078
Claudia CianciDipartimento di Meccanica, Matematica e Management, Politecnico di Bari, Bari, Italy.ORCID 0000-0001-7888-6567
Vimalathithan Paramsamy KannanDipartimento di Meccanica, Matematica e Management, Politecnico di Bari, Bari, Italy.ORCID 0000-0002-9685-1242
Giovanni PappaletteraDipartimento di Meccanica, Matematica e Management, Politecnico di Bari, Bari, Italy.ORCID 0000-0001-6257-5721
Carmine PappalettereDipartimento di Meccanica, Matematica e Management, Politecnico di Bari, Bari, Italy.
Caterina CasavolaDipartimento di Meccanica, Matematica e Management, Politecnico di Bari, Bari, Italy.
Michele LaurenzielloDipartimento di Medicina Sperimentale e Clinica, Università di Foggia, Foggia, Italy.
Domenico CiavarellaDipartimento di Medicina Sperimentale e Clinica, Università di Foggia, Foggia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The widespread adoption of clear aligners in orthodontic treatments in recent years has necessitated a more precise examination of the mechanical properties of the devices currently available in orthodontics. Recent studies indicate that aligners, when exposed to the forces exerted during swallowing, undergo fatigue-like phenomena, leading to chip formation and cracks. The cumulative damage results in a compromised fit between the tooth and aligner, which is crucial for the effective execution of orthodontic treatment. Additionally, the formation of chips poses a potential risk to patients, as there is a possibility of inadvertently ingesting microplastics that become detached from the aligner over time. This study attempts to assess the release of microplastics from the aligners subjected to cyclic compressive loading. Three different aligners (Essix Ace, Ghost Aligner and Invisalign) are tested to simulate swallowing conditions over the aligner usage period. The mechanical performance is studied in terms of the energy absorbed by the aligner, which shows that the Essix Ace has a stable energy absorption behaviour, while the energy absorbed by the Invisalign is significantly higher than their counterparts. Ghost Aligner did not perform well in the cyclic compression tests. The microplastics (MPs) released by the aligners are examined under an optical microscope. A dimensional analysis based on k-means image segmentation and edge detection algorithm is developed to analyse the MPs. The dimensional analysis of the MPs revealed that the ingestion of the MPs released by all the three aligners does not pose a health risk.

Indexed as

MicroplasticsHumansMaterials TestingStress, MechanicalMicroplastics

Identifiers

PMID39908302
PMCPMC11798498

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.