Evidence map›Paper›PMID 39908106›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Ethylene-independent modulation of root development by ACC via downregulation of WOX5 and group I CLE peptide expression.

Wangshu Mou, Ria Khare, Joanna K Polko, Isaiah Taylor, Juan Xu, Dawei Xue, Philip Benfey, Bram Van de Poel, Caren Chang, Joseph J Kieber

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Ethylene-independent modulation of root development by ACC via downregulation of WOX5 and group I CLE peptide expression.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Small signaling peptides define leaf longevity.Frontiers in plant science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wangshu Mou *College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.ORCID 0000-0003-4585-8791
Ria Khare *Department of Biology, University of North Carolina, Chapel Hill, NC 27599.ORCID 0000-0001-6561-4511
Joanna K PolkoDepartment of Biology, University of North Carolina, Chapel Hill, NC 27599.ORCID 0000-0003-2361-4200
Isaiah TaylorDepartment of Biology, Duke University, Durham, NC 27708.ORCID 0000-0002-6535-8658
Juan XuCollege of Life Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0001-6683-6415
Dawei XueCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.ORCID 0000-0001-9904-7615
Philip BenfeyDepartment of Biology, Duke University, Durham, NC 27708.ORCID 0000-0001-5302-758X
Bram Van de PoelDepartment of Biosystems, University of Leuven, Leuven 3001, Belgium.ORCID 0000-0001-5638-2472
Caren ChangDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742.ORCID 0000-0003-0384-5888
Joseph J KieberDepartment of Biology, University of North Carolina, Chapel Hill, NC 27599.ORCID 0000-0002-5766-812X

Funding

FWO Postdoctoral fellowship 1207022 NNational Science Foundation (NSF) IOS-1856431National Science Foundation (NSF) MCB-1714993National Science Foundation (NSF) MCB-2427432Research Foundation Flanders G023124NResearch Foundation Flanders G092419NZhejiang Provincial Natural Science Foundation LQ23C020002
6 · The paper itself

Abstract

In seed plants, the canonical role of 1-aminocyclopropane-1-carboxylic acid (ACC) is to serve as the precursor in the biosynthesis of the phytohormone ethylene, and indeed, ACC treatment is often used as a proxy for ethylene treatment. Increasing evidence suggests that ACC can also act independently of ethylene to regulate various aspects of plant growth and development. Here, we explore the effects of ACC on

Indexed as

Amino Acids, CyclicArabidopsisArabidopsis ProteinsEthylenesGene Expression Regulation, PlantHomeodomain ProteinsPlant RootsDown-RegulationMeristemSignal Transduction1-aminocyclopropane-1-carboxylic acidAmino Acids, CyclicArabidopsis ProteinsAT2G27250 protein, ArabidopsisethyleneEthylenesHomeodomain ProteinsWUSCHEL protein, ArabidopsisACCCLE peptidesethylenelateral rootsroot development

Identifiers

PMID39908106
PMCPMC11831204

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.