Evidence map›Paper›PMID 39907942›Full record

SynthesisQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025

The mere-measurement effect of patient-reported outcomes: a systematic review and meta-analysis.

Preston A Long, Anouk S Huberts, Anouk Neureiter di Torrero, Lisa R Otto, Alizé A Rogge, Valentin Ritschl, Tanja A Stamm

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Preston A LongInstitute for Outcomes Research, Center for Medical Data Science, Medical University of Vienna, Spitalgasse 23, 1090, Wien, Austria. preston.long@meduniwien.ac.at.ORCID http://orcid.org/0000-0002-9752-9570
Anouk S HubertsDepartment of Quality and Patient Care, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.
Anouk Neureiter di TorreroDepartment of Quality and Patient Care, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.
Lisa R OttoCenter for Patient-Centered Outcomes Research, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Alizé A RoggeCenter for Patient-Centered Outcomes Research, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Valentin RitschlInstitute for Outcomes Research, Center for Medical Data Science, Medical University of Vienna, Spitalgasse 23, 1090, Wien, Austria.
Tanja A StammInstitute for Outcomes Research, Center for Medical Data Science, Medical University of Vienna, Spitalgasse 23, 1090, Wien, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe mere-measurement effect is the phenomenon in which subjects exposed to measurements have their perceptions and/or behaviors on the inquired topic affected simply through the act of responding. Patient-reported outcomes (PROs) are increasingly used to assess patient perspective and quality of life in clinical trials and different health care settings. This systematic literature review aims to assess what is currently known about the mere-measurement effect of PROs.

methodsA systematic literature review and meta-analysis was conducted. We included studies that provided evidence on perceptual or behavioral changes in patients as a result of exposure to questionnaire items assessing PROs. All adult participants were included regardless of demographics. Any study design was considered eligible for inclusion. The databases MEDLINE [PubMed], CINAHL [Ebsco], Web of Science and ScienceDirect were searched.

resultsThe search resulted in 636 articles which led to a final extraction of nine. Overall, seven of the nine articles reported a significant main effect, i.e. presence of the mere-measurement effect. For the meta-analysis, thirteen different interventions were included. There was a one-directional, positive and significant overall risk ratio of 1.17 [CI95% 1.04;1.30].

conclusionThis systematic review found significant potential for the mere-measurement effect to shape respondents' behaviors or perceptions for the better, opening the door to the possibility of engineering PROs to serve as a subtle intervention. Future considerations and directions for research are discussed.

Indexed as

Patient Reported Outcome MeasuresQuality of LifeHumansSurveys and QuestionnairesMere-measurement effectPatient-reported outcomesQuestion-behaviour effectSystematic literature review

Identifiers

PMID39907942
PMCPMC12064450

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.