Evidence map›Paper›PMID 39907920›Full record

ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2025

The influence of stress, coping mechanisms and psychological symptoms on inflammatory bowel disease activity: A retrospective case-control analysis.

Javad Shokri Shirvani, Seyed Taher Hashemi Petrodi, Hoda Shirafkan, Shirin Shahrokhi, Mahbobeh Faramarzi

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Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Javad Shokri ShirvaniDepartment of Internal Medicine, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.ORCID 0000-0003-3242-8522
Seyed Taher Hashemi PetrodiStudent Research Committee, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Hoda ShirafkanSocial Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.ORCID 0000-0002-5682-1153
Shirin ShahrokhiClinical Psychology, Student Research Committee, Behshahr Azad University, Behshahr, Iran.ORCID 0000-0003-4227-2998
Mahbobeh FaramarziDepartment of General Courses, Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. mahbob330@yahoo.com.ORCID 0000-0002-3568-7039

Funding

Babol University of Medical Sciences 724133947
6 · The paper itself

Abstract

BACKGROUND AND

objectivesPsychological stress is widely recognized as a key factor that can initiate or aggravate symptoms in patients with inflammatory bowel disease (IBD). This research was aimed at examining the influence of stressors, coping mechanisms and psychological symptoms on disease activity in patients with Crohn's disease (CD) and ulcerative colitis (UC).

methodsA retrospective case-control research was performed with 138 patients diagnosed with IBD (76 with CD and 62 with UC). The participants were categorized into case groups (active disease: 31 CD, 38 UC) and control groups (inactive disease: 31 CD, 38 UC), with matching on demographic and clinical characteristics. Each participant completed several assessments such as the Simple Clinical Colitis Activity Index (SCCAI), the Harvey-Bradshaw index (HBI), the Life Distress Inventory (LDI), the Symptom Checklist (SCL-25) and the Coping Inventory for Stressful Situations (CISS-21).

resultsParticipants experiencing active disease reported higher levels of life stress, with mean scores of 65.42 ± 8.88 in CD and 65.42 ± 8.88 in UC, in comparison with 45.97 ± 13.23 and 41.79 ± 13.49, respectively, in those with inactive disease. Additionally, psychological symptoms were more prevalent in both CD group (57.00 ± 12.71 vs. 47.39 ± 14.65) and the UC group (57.80 ± 9.82 vs. 40.05 ± 11.23) with active disease. Patients with active disease were more likely to employ coping strategies centered on avoidance, emotional responses and tasks than those without disease activity. Logistic regression analysis identified life stress (p < 0.001, 95% CI = [1.06-1.18], B = 1.24) and emotion-focused coping strategies (p < 0.001, 95% CI = [1.26-1.88], B = 1.54) as notable predictors of disease activity, whereas task-focused coping emerged as a protective factor (p < 0.029, 95% CI = [1.68-1.98], B = 1.81).

conclusionThis research underscores the critical role of managing stress and adopting effective coping mechanisms in reducing the likelihood of disease flare-ups in IBD subjects. Healthcare providers should prioritize integrating these approaches into treatment protocols for IBD management.

Indexed as

Adaptation, PsychologicalColitis, UlcerativeCrohn DiseaseInflammatory Bowel DiseasesStress, PsychologicalAdultCase-Control StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesSeverity of Illness IndexYoung AdultCoping stylesDisease activityInflammatory bowelPsychological symptomsStress

Identifiers

PMID39907920

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