Evidence map›Paper›PMID 39907912›Full record

ArticleRheumatology and therapy2025

Factors Influencing Treatment Satisfaction and Recognition Gaps Between Physicians and Patients with Systemic Sclerosis.

Yoshihito Shima, Mona Uchida-Yamada, Sei-Ichiro Motegi, Taku Shimada, Haruka Ishii, Yoshito Ohya, Yasumasa Kanai

Abstract read
In one paragraph

Article in Rheumatology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yoshihito ShimaLaboratory of Thermo-Therapeutics for Vascular Dysfunction, Osaka University Graduate School of Medicine, Osaka, Japan.ORCID http://orcid.org/0000-0002-2523-2938
Mona Uchida-YamadaMedical Affairs, Kyowa Kirin Co., Ltd., Tokyo, Japan.ORCID http://orcid.org/0000-0002-5781-9485
Sei-Ichiro MotegiDepartment of Dermatology, Gunma University Graduate School of Medicine, Maebashi, Japan.ORCID http://orcid.org/0000-0001-8286-0669
Taku ShimadaMedical Affairs, Kyowa Kirin Co., Ltd., Tokyo, Japan.
Haruka IshiiMedical Affairs, Kyowa Kirin Co., Ltd., Tokyo, Japan.
Yoshito OhyaMedical Affairs, Kyowa Kirin Co., Ltd., Tokyo, Japan.
Yasumasa KanaiMedical Affairs, Kyowa Kirin Co., Ltd., Tokyo, Japan. yasumasa.kanai.xg@kyowakirin.com.ORCID http://orcid.org/0009-0005-0300-4917

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIt is important to understand the differences in patient-physician perceptions and factors affecting satisfaction with treatment in patients with systemic sclerosis (SSc).

methodsThis web-based survey (conducted in Japan in March 2023) targeted patients aged ≥ 18 years with SSc and physicians in hospitals with ≥ 20 beds and seeing ≥ 3 patients with SSc monthly. Physicians and patients answered similar questions.

resultsResponders were 301 patients (63.8% female; 47.5% limited cutaneous SSc; 44.9% diffuse cutaneous SSc) and 129 physicians (51.2% rheumatologists; 20.9% dermatologists). The most common problematic symptoms reported by patients having each symptom were Raynaud's phenomenon (RP) (59.5%), skin tightening (47.4%), and malaise (45.5%). Physicians also perceived RP as the common problematic symptoms (46.5%). Conversely, there was a large gap in the perception of malaise as problematic (5.4%). There was a ≥ 20% difference in the percentage of respondents who felt that treatments improved symptoms of reflux esophagitis (48.8% in patients vs. 76.7% in physicians), dysphagia (25.0% vs. 52.7%), constipation (35.1% vs. 62.8%), diarrhea (36.1% vs. 62.8%), and pain (47.6% vs. 69.0%). Patient characteristics associated with high satisfaction with treatment included treatment responsiveness, age ≥ 50 years, being anti-topoisomerase I antibody positive, having dermatological or digestive symptoms as problematic symptoms, and not feeling they should have seen their physician earlier.

conclusionsPatients and physicians had different perceptions of symptoms and treatment response. Patients' perception of improvement affected their satisfaction with treatment. Reviewing treatment goals and content between patients and physicians is necessary to improve treatment satisfaction.

trial registrationUMIN000050368.

Indexed as

Needs assessmentPatient-reported outcomeQuestionnaireSurveySystemic scleroderma

Identifiers

PMID39907912
PMCPMC11920495

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.