Evidence map›Paper›PMID 39907858›Full record

ReviewHead and neck pathology2025

Intraoral Lymphomatoid Papulosis Type D Showing Scarce/Absent CD30 Expression in A Pediatric Patient: Case Report and Literature Review.

Mariana Paravani Palaçon, Marcelo Borges Marques, Débora Fernandes Mendes Silveira, Karina Helen Martins, Heitor Albergoni Silveira, Valfrido Antonio Pereira-Filho, Andreia Bufalino, Fernando Chahud, Jorge Esquiche León

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In one paragraph

Review in Head and neck pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mariana Paravani PalaçonDepartment of Diagnosis and Surgery, Araraquara Dental School, FOAr/UNESP, Araraquara, São Paulo, Brazil.
Marcelo Borges MarquesDepartment of Diagnosis and Surgery, Araraquara Dental School, FOAr/UNESP, Araraquara, São Paulo, Brazil.
Débora Fernandes Mendes SilveiraDepartment of Diagnosis and Surgery, Araraquara Dental School, FOAr/UNESP, Araraquara, São Paulo, Brazil.
Karina Helen MartinsOral Pathology, Department of Stomatology, Public Oral Health, and Forensic Dentistry, Ribeirão Preto Dental School (FORP/USP), University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Heitor Albergoni SilveiraDepartment of Pathology and Forensic Medicine, Ribeirão Preto Medical School (FMRP/USP), University of São Paulo, Ribeirão Preto, São Paulo,, Brazil.
Valfrido Antonio Pereira-FilhoDepartment of Diagnosis and Surgery, Araraquara Dental School, FOAr/UNESP, Araraquara, São Paulo, Brazil.
Andreia BufalinoDepartment of Diagnosis and Surgery, Araraquara Dental School, FOAr/UNESP, Araraquara, São Paulo, Brazil.
Fernando ChahudDepartment of Pathology and Forensic Medicine, Ribeirão Preto Medical School (FMRP/USP), University of São Paulo, Ribeirão Preto, São Paulo,, Brazil.
Jorge Esquiche LeónDepartment of Pathology and Forensic Medicine, Ribeirão Preto Medical School (FMRP/USP), University of São Paulo, Ribeirão Preto, São Paulo,, Brazil. jleon@forp.usp.br.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico (304241/2021-0)Fundação de Amparo à Pesquisa do Estado de São Paulo (2016/11419-0; 2022/07479-9 and 2022/12760-9)
6 · The paper itself

Abstract

purposeApproximately 10% of all lymphomatoid papulosis (LyP) cases affect pediatric patients. Pediatric LyP is clinically similar to adult LyP, frequently with cutaneous involvement, whereas the affectation of mucosal surface is rare. The LyP clinicopathological spectrum includes type A, B, C, D, E, and LyP with DUSP22/IRF4 rearrangement, with LyP type D representing < 5% of all LyP cases.

methodsWe have previously reported 2 cases of exclusively intraoral LyP type C and E. To date, about 50 cases of LyP type D have been reported; of them, 8 cases, all but one with exclusive skin involvement, corresponded to pediatric patients. Rare LyP type C cases can lack CD30 expression, creating diagnostic difficulties with lymphoma.

resultsHere, we report an extremely rare case of intraoral LyP type D with scarce/absent CD30 expression affecting a 12-year-old white Brazilian boy.

conclusionsTo our best knowledge, this is the first pediatric case of LyP type D with exclusive intraoral involvement.

Indexed as

Ki-1 AntigenLymphomatoid PapulosisMouth NeoplasmsBiomarkers, TumorChildHumansMaleBiomarkers, TumorKi-1 AntigenCD30Differential diagnosisLymphomatoid papulosis type DOral cavityPediatric patients

Identifiers

PMID39907858
PMCPMC11799464

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