SynthesisExperimental brain research2025
Acute effects of anodal transcranial direct current stimulation on endurance and maximal voluntary contraction in lower limbs: a systematic review and meta-analysis.
Synthesis in Experimental brain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Acute effects of anodal transcranial direct current stimulation on maximal voluntary force, repeated maximal isometric contractions and corticospinal excitability in healthy young adults.European journal of applied physiology · 2026Trial
- Effects of transcranial direct current stimulation (tDCS) on isometric endurance performance and electromyographic activity of the vastus lateralis in healthy male.Experimental brain research · 2025Article
- Multifocal tDCS targeting lower-limb cortical areas preserves late-stage endurance and tunes phase-specific coordination during incremental cycling.Frontiers in physiology · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo examine the effects of single-dose anodal tDCS on isometric maximal voluntary contraction (MVC) and isometric endurance performance in lower limb exercises with healthy adults.
methodsFor this systematic review and meta-analysis, we searched PubMed, ISI Web of Science, Scopus, and CINAHL for studies published between database inception and June 11, 2024. All randomized controlled trials on anodal tDCS interventions for MVC and isometric endurance in lower limb exercises were included, with no date restrictions. The quality of the evidence was assessed using the Jadad Scale, and the certainty of evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation approach. The Open Science Framework registered the protocol in June 2024 (DOI https://doi.org/10.17605/OSF.IO/AG93M ).
results20 interventions were included, comprising 15 for MVC and 5 for 'Time to Task Failure' (TTF), which refers to isometric endurance performance measured in seconds. The findings showed no difference in the MVC (SMD = 0.06; 95% CI = - 0.14, 0.25; P = 0.57) and TTF performance (WMD = 0.07; 95% CI = - 0.26, 0.40; P = 0.68).
conclusionThe current meta-analysis indicated that anodal tDCS did not increase isometric MVC and isometric endurance performance in lower limb exercises in healthy adults.
Indexed as
Identifiers
39907829What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.