ArticleSkeletal radiology2025
Sex differences in photon-counting detector computed tomography-derived scaphotrapeziotrapezoid joint morphometrics.
Article in Skeletal radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Rapid personalized computational modeling of the wrist.Medical engineering & physics · 2026Article
- Artificial Intelligence Models for Classifying Wrist Ligament Injuries Using Synthetically-Generated Joint Proximity Maps from Finite Element Models.bioRxiv : the preprint server for biology · 2026Article
- Finite Element Modeling of the Scaphoid Shift Maneuver: Implications for Scapholunate Ligament injuries.bioRxiv : the preprint server for biology · 2026Article
- Shape predicts osteoarthritis progression in the first carpometacarpal joint.Frontiers in bioengineering and biotechnology · 2026Article
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Authors and funding
8 authors.
Funding
Abstract
objectiveThe scaphotrapeziotrapezoid (STT) joint transmits load between the wrist and thumb. Despite its clinical importance, it has received less diagnostic attention than adjacent wrist and thumb joints. CT-derived three-dimensional models offer the ability to improve measurement of articular space by evaluating subchondral articular surfaces, which can be quantified using articular morphometrics. The objectives of this study were to investigate whether articular surface areas, interosseous proximities, and carpal bone positions differ between sexes. MATERIALS AND
methodsThirty participants (50% female, median age 27.0 years) were prospectively recruited to a cohort study of normative wrist imaging and biomechanics. Carpal bones were meshed from CT-based segmentations using a marching cubes algorithm. Rigid body kinematic parameters of individual bones were calculated. Carpal bone postures were defined using projection angles between bone centroids. Articular surface areas and interosseous proximity distributions between adjacent bones were calculated. Morphometrics were compared between sexes using Wilcoxon rank sum or two-tailed Kolmogorov-Smirnov tests as appropriate.
resultsMedian articular surface area was significantly smaller in females than in males at the trapeziotrapezoid but not scaphotrapezium or scaphotrapezoid joints. Interosseous proximity distributions were closer in females at all joints (scaphotrapezium, 1.19 versus 1.42 mm; scaphotrapezoid, 1.15 versus 1.43 mm; trapeziotrapezoid, 0.45 versus 0.65 mm). Distal bones were more dorsally translated in females.
conclusionThis study quantifies sex-stratified morphological variations at the STT joint. Interosseous proximity distributions may guide interpretation of imaging-derived STT joint space and can serve as reference ranges for studies of STT arthrokinematics.
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