Evidence map›Paper›PMID 39907359›Full record

ArticleCoDAS2025

Voice handicap, vocal fatigue, and voice-related quality of life in patients with multiple sclerosis.

Raí Dos Santos Santiago, Jaya Miranda Carvalho de Araújo, Márcia Helena Cassago Nascimento, Carolina Fiorin Anhoque, Alana Tagarro Neves, Gabriel Trevizani Depolli, Bruno Batitucci Castrillo, Paula Zago Melo Dias, Regina Eliza Albano Vanzo, Carla Carvalho Nascimento and 2 more

Abstract read
In one paragraph

Article in CoDAS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Raí Dos Santos SantiagoUniversidade Federal do Espírito Santo - UFES - Vitória (ES), Brasil.ORCID http://orcid.org/0009-0004-7183-5766
Jaya Miranda Carvalho de AraújoUniversidade Federal do Espírito Santo - UFES - Vitória (ES), Brasil.ORCID http://orcid.org/0009-0002-3806-2218
Márcia Helena Cassago NascimentoUniversidade Federal do Espírito Santo - UFES - Vitória (ES), Brasil.ORCID http://orcid.org/0000-0001-5252-586X
Carolina Fiorin AnhoqueUniversidade Federal do Espírito Santo - UFES - Vitória (ES), Brasil.ORCID http://orcid.org/0000-0003-0855-596X
Alana Tagarro NevesUniversidade Federal do Espírito Santo - UFES - Vitória (ES), Brasil.ORCID http://orcid.org/0000-0002-9215-3017
Gabriel Trevizani DepolliUniversidade Federal de São Paulo - UNIFESP - São Paulo (SP), Brasil.ORCID http://orcid.org/0000-0001-6969-1418
Bruno Batitucci CastrilloHospital Universitário Cassiano Antonio Moraes - HUCAM - Vitória (ES), Brasil.ORCID http://orcid.org/0009-0006-5081-7045
Paula Zago Melo DiasHospital Universitário Cassiano Antonio Moraes - HUCAM - Vitória (ES), Brasil.ORCID http://orcid.org/0000-0002-0770-2385
Regina Eliza Albano VanzoHospital Universitário Cassiano Antonio Moraes - HUCAM - Vitória (ES), Brasil.ORCID http://orcid.org/0009-0003-3078-0562
Carla Carvalho NascimentoHospital Universitário Cassiano Antonio Moraes - HUCAM - Vitória (ES), Brasil.ORCID http://orcid.org/0009-0003-2205-0340
Valerio Garrone BaraunaUniversidade Federal do Espírito Santo - UFES - Vitória (ES), Brasil.ORCID http://orcid.org/0000-0003-2832-0922
Lívia Carla de Melo RodriguesUniversidade Federal do Espírito Santo - UFES - Vitória (ES), Brasil.ORCID http://orcid.org/0000-0002-6004-7981

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeto describe sociodemographic characteristics of individuals with multiple sclerosis and correlate and compare vocal fatigue, voice handicap, and voice-related quality of life of individuals with and without the disease.

methodsCross-sectional, quantitative study with 52 volunteers with multiple sclerosis and 52 control volunteers, matched by sex, age, and education level. Sociodemographic and clinical data were collected through a questionnaire and medical record analysis. Participants responded to the reduced Voice Handicap Index (VHI-10), Vocal Fatigue Index (VFI), and Voice-Related Quality of Life (V-RQOL). Correlational and comparative analyses were performed, with a 5% significance level (p < 0.05).

resultsThere was a greater predominance of females diagnosed with multiple sclerosis, with a mean age of 40 years, who graduated from high school, and with a relapsing-remitting disease course. Voice handicap was positively correlated with vocal fatigue, and voice handicap and vocal fatigue were negatively correlated with voice-related quality of life in both groups. Participants with multiple sclerosis exceeded the VHI-10 and VFI cutoff scores and were below the V-RQOL cutoff score.

conclusionThere was a prevalence of the disease in young, educated females with relapsing-remitting disease. The greater the voice handicap and/or vocal fatigue, the lower the voice-related quality of life in both groups. However, people with multiple sclerosis self-reported greater voice handicap and vocal fatigue and poorer voice-related quality of life.

Indexed as

Multiple SclerosisQuality of LifeVoice DisordersVoice QualityAdultCase-Control StudiesCross-Sectional StudiesFemaleHumansMaleMiddle AgedSeverity of Illness IndexSurveys and QuestionnairesYoung Adult

Identifiers

PMID39907359
PMCPMC11801195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.