Evidence map›Paper›PMID 39907220›Full record

ArticleTranslational behavioral medicine2025

Stakeholder-informed refinement of a behavioral sleep/circadian intervention for gynecologic cancer survivors: an application of the MOST preparation phase.

Rina S Fox, Krista Brandon, Terry A Badger, Julia S Gaumond, Ana Acuña Morales, Jason C Ong, Sairam Parthasarathy, Christine Rini, Phyllis C Zee, Edward J Tanner and 6 more

Abstract read
In one paragraph

Article in Translational behavioral medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Rina S FoxDivision of Nursing and Health Science, University of Arizona College of Nursing, 1305 N. Martin Avenue, Tucson, AZ 85721, USA.ORCID 0000-0003-4307-5259
Krista BrandonDivision of Nursing and Health Science, University of Arizona College of Nursing, 1305 N. Martin Avenue, Tucson, AZ 85721, USA.
Terry A BadgerDivision of Nursing and Health Science, University of Arizona College of Nursing, 1305 N. Martin Avenue, Tucson, AZ 85721, USA.
Julia S GaumondVanderbilt University School of Medicine, 1161 21st Avenue S # D3300, Nashville, TN 37232, USA.
Ana Acuña MoralesDivision of Nursing and Health Science, University of Arizona College of Nursing, 1305 N. Martin Avenue, Tucson, AZ 85721, USA.
Jason C OngNox Health, 100 Kimball Place, Alpharetta, GA 30009,USA.
Sairam ParthasarathyDivision of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, University of Arizona College of Medicine - Tucson, 1501 N. Campbell Avenue, Tucson, AZ 85724, USA.
Christine RiniDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, 625 N. Michigan Avenue 21st Floor, Chicago, IL 60611,USA.
Phyllis C ZeeDepartment of Neurology, Northwestern University Feinberg School of Medicine, 710 N. Lake Shore Drive 11th Floor, Chicago, IL 60611, USA.
Edward J TannerRobert H. Lurie Comprehensive Cancer Center of Northwestern University, 675 N St Clair Street 21st Floor Chicago, IL 60611, USA.
Sonia Ancoli-IsraelDepartment of Psychiatry, University of California, San Diego, 3120 Biomedical Sciences Way, La Jolla, CA 92093, USA.
Frank J PenedoDepartments of Medicine and Psychology and Sylvester Comprehensive Cancer Center, University of Miami, 1475 NW 12th Avenue Miami, FL 33136, USA.
Juned SiddiqueDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, 680 N. Lake Shore Drive Suite 1400, Chicago, IL 60611, USA.
Lisa M WuDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, 625 N. Michigan Avenue 21st Floor, Chicago, IL 60611,USA.
Kathryn J ReidDepartment of Neurology, Northwestern University Feinberg School of Medicine, 710 N. Lake Shore Drive 11th Floor, Chicago, IL 60611, USA.
Karen KaiserDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, 625 N. Michigan Avenue 21st Floor, Chicago, IL 60611,USA.

Funding

VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Rachna Shroff · 1985 to 2026
$110.2M
Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
NUCATS CTSA UM1 at Northwestern UniversityUM1TR005121 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Sara Becker, Richard D'Aquila · 2024 to 2026
$23.4M
Improving sleep in gynecologic cancer survivorsK08CA247973 · NCI · UNIVERSITY OF ARIZONA · PI FOX, RINA S · 2021 to 2025
$926k
NCATS NIH HHS UL1 TR001422NCATS NIH HHS UL1TR001422NCATS NIH HHS UM1 TR005121NCI NIH HHS K08 CA247973NCI NIH HHS K08CA247973NCI NIH HHS P30 CA023074NIH HHSUniversity of Arizona College of Nursing
6 · The paper itself

Abstract

backgroundSleep disturbance is among the most frequent and distressing symptoms reported by gynecologic cancer survivors. Existing evidence-based behavioral sleep interventions are limited by implementation burden, which can decrease adherence. PURPOSE: As part of the preparation phase of the multiphase optimization strategy (MOST), this study solicited stakeholder feedback to maximize adherence in a planned behavioral sleep/circadian intervention optimization trial.

methodsThirteen post-treatment survivors of early-stage gynecologic cancer completed the protocol for the planned optimization trial, including simultaneous receipt of all candidate intervention components. This included six weeks of combined sleep restriction, stimulus control, and systematic exposure to morning bright light. Participants then completed a semi-structured interview to provide feedback on their experience. We used a rapid analytic approach to quickly identify actionable feedback from de-identified transcripts.

resultsParticipants generally reacted positively to the intervention components. Actionable feedback identified recommended protocol modifications and was categorized into four overarching themes: (i) remove barriers to engagement; (ii) revise for clarity; (iii) augment content; and (iv) consider individual circumstances.

conclusionsRapid qualitative analysis enabled us to effectively modify our planned study protocol on an expedited timeline. This approach is consistent with the core principles of MOST and can be incorporated into the Preparation phase to enhance optimization efforts.

Indexed as

Behavior TherapyCancer SurvivorsGenital Neoplasms, FemaleSleepSleep Wake DisordersAdultAgedFemaleHumansMiddle AgedStakeholder Participationgynecologic cancerMultiphase optimization strategyrapid qualitative analysissleep

Identifiers

PMID39907220
PMCPMC11795304

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.