ArticleJournal of public health (Oxford, England)2025
Sex differences in the impact of multimorbidity on long-term mortality for patients with colorectal cancer: a population registry-based cohort study.
Article in Journal of public health (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Patterns of Multimorbidity among Older Adults with Colorectal Cancer Living in Puerto Rico.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026Article
- Comorbidity patterns and risk of breast cancer: a case-control study exploring interaction with BMI using latent class analysis.Frontiers in oncology · 2026Article
- Article
- Are Colon Polyp Characteristics Really Different Between Men and Women?JGH open : an open access journal of gastroenterology and hepatology · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundWomen have better survival than men patients with colorectal cancer (CRC), but the extent to which this is due to multimorbidity is unclear.
methodsA population-based study of 1843 patients diagnosed with CRC in Australia. Data included patient's demographics, multimorbidity, tumour histology, cancer stage, and treatment. We estimated the risks of all-cause mortality and cause-specific mortality due to cancer or non-cancer causes.
resultsMen had lower survival than women (P ≤ 0.010) amongst those diagnosed at Stages I-III (15-year survival: 56.0% vs 68.0%, 48.5% vs 60.7%, 34.8% vs 47.5%, respectively), excepting Stage IV (14.4% vs 12.6%; P = 0.18). Married men exhibit better survival than those who were never married (P = 0.006). Heart attacks (9.9% vs 4.3%, P < 0.001) and emphysema (4.8% vs 2.1%, P = 0.004) were more prevalent in men than women. Comorbid stroke and high cholesterol (adjusted hazard ratio, AHR = 2.22, 95% confidence interval, CI = 1.17-4.21, P = 0.014) and leukaemia (AHR = 6.36, 95% CI = 3.08-13.1, P < 0.001) increased the risk of cancer death for men only. For women, diabetes increased the risk of all-cause death (AHR = 1.38, 95% CI = 1.02-1.86, P = 0.039) and high blood pressure increased the risk of death due to non-cancer causes (AHR = 2.00, 95% CI = 1.36-2.94, P < 0.001).
conclusionSeparate models of CRC care are needed for men and women with consideration of multimorbidity and social factors.
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