Evidence map›Paper›PMID 39907002›Full record

ArticlePest management science2025

EPSPS target site mechanisms confer glyphosate resistance in Arctotheca calendula.

Norazua Zakaria, Heping Han, Yaseen Khalil, Michael Ashworth, Qin Yu, Ken C Flower

Abstract read
In one paragraph

Article in Pest management science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Norazua ZakariaDepartment of Crop Science, Faculty of Agriculture, Universiti Putra Malaysia, Serdang, Malaysia.ORCID https://orcid.org/0000-0001-9890-0223
Heping HanAustralian Herbicide Resistance Initiative, School of Agriculture & Environment, University of Western Australia, Perth, Western Australia, Australia.ORCID https://orcid.org/0000-0002-0918-2598
Yaseen KhalilAustralian Herbicide Resistance Initiative, School of Agriculture & Environment, University of Western Australia, Perth, Western Australia, Australia.
Michael AshworthAustralian Herbicide Resistance Initiative, School of Agriculture & Environment, University of Western Australia, Perth, Western Australia, Australia.ORCID https://orcid.org/0000-0002-9141-7404
Qin YuAustralian Herbicide Resistance Initiative, School of Agriculture & Environment, University of Western Australia, Perth, Western Australia, Australia.ORCID https://orcid.org/0000-0001-6379-9444
Ken C FlowerAustralian Herbicide Resistance Initiative, School of Agriculture & Environment, University of Western Australia, Perth, Western Australia, Australia.

Funding

Grains Research and Development Corporation (GRDC)The Ministry of Higher Education, Malaysia and Universiti Putra Malaysia
6 · The paper itself

Abstract

backgroundThe first case of glyphosate resistance was reported in a capeweed population from Western Australia in our previous study. This current study investigates the resistance mechanisms in the population.

resultsTarget-site EPSPS gene sequencing revealed two partial sequences of the EPSPS transcripts (1001 bp and 998 bp), and the full-length sequence (1551 bp) containing the 1001-bp transcript was cloned as it was found in the resistant plants. A known resistance-endowing target-site mutation in the 1551-bp transcript was identified in the resistant plants, resulting in the Pro-106-Ser substitution. The subpopulation derived from these mutant plants exhibited >10-fold resistance to glyphosate compared to the susceptible population. Additionally, the EPSPS gene (1551 bp) was constitutively expressed at a higher level (4.3-fold) in the resistant than in the susceptible populations. However,

conclusionGlyphosate resistance in the studied population is associated with both a target-site mutation (Pro-106-Ser) and increased EPSPS gene expression. © 2025 The Author(s). Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

3-Phosphoshikimate 1-CarboxyvinyltransferaseGlycineHerbicide ResistanceHerbicidesPlant ProteinsGlyphosateMutation3-Phosphoshikimate 1-CarboxyvinyltransferaseGlycineGlyphosateHerbicidesPlant ProteinscapeweedEPSPSglyphosate‐resistancetarget‐site resistance

Identifiers

PMID39907002
PMCPMC12074620

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.