Evidence map›Paper›PMID 39906920›Full record

ArticleACR open rheumatology2025

Social Connections in Older Adults With Systemic Lupus Erythematosus: Patient Perspectives.

Sarah B Lieber, Sarah R Young, Yvonne Shea, Sarah P Gottesman, Robyn Lipschultz, Dongmei Sun, M Carrington Reid, Lisa A Mandl, Iris Navarro-Millán

Abstract read
In one paragraph

Article in ACR open rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sarah B LieberHospital for Special Surgery and Weill Cornell Medicine, New York, New York.ORCID https://orcid.org/0000-0002-6176-9740
Sarah R YoungWeill Cornell Medicine, New York, New York.
Yvonne SheaHospital for Special Surgery, New York, New York.
Sarah P GottesmanHospital for Special Surgery, New York, New York.
Robyn LipschultzNew York University Grossman School of Medicine, New York.ORCID https://orcid.org/0009-0000-9091-8947
Dongmei SunHospital for Special Surgery, New York, New York.
M Carrington ReidWeill Cornell Medicine, New York, New York.
Lisa A MandlHospital for Special Surgery and Weill Cornell Medicine, New York, New York.ORCID https://orcid.org/0000-0001-6085-8664
Iris Navarro-MillánHospital for Special Surgery and Weill Cornell Medicine, New York, New York.ORCID https://orcid.org/0000-0002-9540-6614

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Pilot CoreP30AG022845 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Manney Carrington Reid, ELAINE WETHINGTON · 2003 to 2026
$15.2M
Institutional Career Development CoreKL2TR002385 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI YUAN-SHAN ZHU · 2017 to 2026
$13.3M
Reid Aging and Pain Research Training ProgramK24AG053462 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI REID, MANNEY CARRINGTON · 2016 to 2025
$1.8M
Hospital for Special Surgery Fund for the FutureNCATS NIH HHS KL2 TR002385NCATS NIH HHS KL2TR002385NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002384NCATS NIH HHS UL1TR002384NIA NIH HHS K24 AG053462NIA NIH HHS K24AG053462NIA NIH HHS P30 AG022845
6 · The paper itself

Abstract

objectiveInterpersonal relationships are crucial to healthy aging. Social isolation is associated with multiple adverse health outcomes in older adults, including depression. Those with chronic conditions, such as systemic lupus erythematosus (SLE), may be particularly vulnerable to social isolation. In this qualitative study, we elicited lived experiences of older adults with SLE related to social connections and emotional health.

methodsAdults ≥65 years of age with SLE participated in semistructured interviews based on a descriptive phenomenological design to describe the experience of aging with SLE. We collected self-reported data on sociodemographic and disease characteristics, social networks, and health-related quality of life. We probed participants regarding their interpersonal relationships and the effect of SLE on general health in the context of aging. We analyzed qualitative data thematically.

resultsAmong 30 participants with a mean age of 71.3 years, three themes emerged as essential to characterizing aging with SLE: (1) social isolation, (2) perceived burden to loved ones, and (3) adverse mental health effects of SLE. Participants frequently reported social isolation, often related to SLE disease manifestations rather than unavailability of social networks and situated within the context of burdening loved ones and mental health effects of SLE.

conclusionSocial isolation was commonly reported by older adults with SLE. Larger observational studies are needed to improve characterization of social isolation in this population and understand its association with depression and other adverse health outcomes. Investigational studies integrating strategies to improve social isolation in older adults with SLE may improve their health and well-being.

Identifiers

PMID39906920
PMCPMC11795054

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.