ReviewHeliyon2025
Different catalytic approaches of Friedländer synthesis of quinolines.
Review in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Recent Advances in Quinoline Synthesis: Sustainable Catalytic Strategies and Emerging Methodologies.Molecules (Basel, Switzerland) · 2026Review
- Synthesis of Antimicrobial Quinoline Derivatives Enabled by Synergistic Pd/Enamine Catalysis: Experimental and Computational Study.Precision chemistry · 2026Article
- Traditional and Sustainable Methods for the Synthesis of Quinoline Derivatives as Anticancer Agents (2019-Present): A Comprehensive Review.Anti-cancer agents in medicinal chemistry · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Friedländer quinoline synthesis is one of the most important and simplest methods among the various reported methodologies for quinoline synthesis, renowned for its efficiency and versatility. The reaction involves the condensation of a 2-aminobenzaldehyde with a ketone, forming polysubstituted quinolines. This review comprehensively examined diverse catalytic approaches developed to optimize the Friedländer reaction, highlighting recent advancements and their impact on reaction efficiency, selectivity, and environmental sustainability. The discussion encompassed traditional catalysts and emerging catalytic systems, including ionic liquids, metal-organic frameworks, polymers, and nanocatalysts. Additionally, the review addresses the influence of various catalytic environments on reaction outcomes. By collating and critically analyzing recent advancements, this review aims to provide a valuable resource for researchers seeking to leverage these catalytic strategies for synthesizing quinoline derivatives.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.