Unveiling the burden of premenstrual dysphoric disorder: a narrative review to call for gender perspective and intersectional approaches.

The present narrative review discusses the burden of Premenstrual Dysphoric Disorder (PMDD) and highlights the lack of awareness by analyzing the following key points: -Prevalence and Diagnosis: PMDD affects a significant portion of women during their reproductive years, but diagnosis is often delayed due to limited understanding and awareness. -Mental Health Burden: PMDD increases the risk of suicide attempts and negatively impacts quality of life. There are also economic costs associated with absenteeism and healthcare use. -Cultural and Gender Perspectives: Societal stigma surrounding menstruation and mental health likely contributes to underdiagnosis. -Lack of Sex and Gender Perspective in the Healthcare System: Research bias towards male subjects and historical neglect of women's health issues contribute to limited knowledge about PMDD. -Non-Intersectional Approaches: Disparities in access to healthcare and the unique experiences of women further complicate PMDD diagnosis and treatment. -Vicious Cycle: The lack of research and awareness creates a vicious cycle where PMDD remains misunderstood and inaccurately treated. Finally, it emphasizes the need for increased awareness, education, and research on PMDD, particularly with a gendered and intersectional optic. The situation in Latin America is presented as a particular concern due to a lack of recent data and potentially higher prevalence due to socioeconomic factors.