Evidence map›Paper›PMID 39906616›Full record

ArticleIranian journal of basic medical sciences2025

Scopolamine-induced memory impairment in mice: Soursop leaf extract and fractions protect the hippocampus and prefrontal cortex.

Faith Afolabi, Babatunde Adebola Alabi, Joseph Ayo Badejo, Okim Okim Nsor, Sodiq Kolawole Lawal, Ezekiel Olugbenga Iwalewa

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of basic medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Faith AfolabiNeuropharmacology Unit, Department of Pharmacology and Therapeutics, Faculty of Basic Medical Sciences, College of Medicine, University.
Babatunde Adebola Alabiof Ibadan, Ibadan, Oyo State, Nigeria.
Joseph Ayo BadejoNeuropharmacology Unit, Department of Pharmacology and Therapeutics, Faculty of Basic Medical Sciences, College of Medicine, University.
Okim Okim NsorNeuropharmacology Unit, Department of Pharmacology and Therapeutics, Faculty of Basic Medical Sciences, College of Medicine, University.
Sodiq Kolawole LawalDepartment of Pharmacology & Therapeutics, Faculty of Medicine and Pharmacy, Kampala International University in Tanzania, Dar Es Salaam.
Ezekiel Olugbenga IwalewaNeuropharmacology Unit, Department of Pharmacology and Therapeutics, Faculty of Basic Medical Sciences, College of Medicine, University.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Materials and Methods: The crude extract was fractionated with n-hexane, ethyl acetate, and aqueous methanol. The crude and fractions were tested Results: The AMME and AMAMF significantly reduced the serum levels of myeloperoxidase and arginine ( Conclusion: The study showed the neuroprotective effects of AMME and AMAMF in memory impairment models. The extracts showed potent AChE inhibition and positive effects on memory and anti-oxidant enzyme levels.

Indexed as

AcetylcholinesteraseGlutamic acidInflammatory mediatorsMemory impairmentThin-layer chromatography

Identifiers

PMID39906616
PMCPMC11790190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.