Evidence map›Paper›PMID 39906590›Full record

ArticleInflammatory intestinal diseases

A Pilot Study Using a Smartwatch to Search for Biomarkers of Heart Rate Variability in Active Ulcerative Colitis.

Jin Imai, Masashi Ohno, Masaya Sano, Takuro Miyazaki, Hiroaki Suzuki, Atsushi Nishida, Yuto Hashida, Takashi Ueda, Haruhiko Sato, Erika Teramura and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Inflammatory intestinal diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Jin ImaiDepartment of Clinical Health Science, Tokai University School of Medicine, Isehara, Japan.
Masashi OhnoDivision of Gastroenterology, Shiga University of Medical Science, Otsu, Japan.
Masaya SanoDivision of Gastroenterology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan.
Takuro MiyazakiGoodTe, Inc. Tokyo, Japan.
Hiroaki SuzukiGoodTe, Inc. Tokyo, Japan.
Atsushi NishidaDivision of Gastroenterology, Shiga University of Medical Science, Otsu, Japan.
Yuto HashidaDepartment of Clinical Health Science, Tokai University School of Medicine, Isehara, Japan.
Takashi UedaDivision of Gastroenterology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan.
Haruhiko SatoDivision of Gastroenterology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan.
Erika TeramuraDivision of Gastroenterology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan.
Makiko MonmaDivision of Gastroenterology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan.
Mia FujisawaDivision of Gastroenterology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan.
Ryuzo DeguchiDivision of Gastroenterology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan.
Nagamu InoueDepartment of Clinical Health Science, Tokai University School of Medicine, Isehara, Japan.
Noriaki KishimotoDepartment of Clinical Health Science, Tokai University School of Medicine, Isehara, Japan.
Akiyasu BabaDepartment of Clinical Health Science, Tokai University School of Medicine, Isehara, Japan.
Masashi MatsushimaDivision of Gastroenterology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan.
Tatehiro KagawaDivision of Gastroenterology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan.
Yasuhiro NishizakiDepartment of Clinical Health Science, Tokai University School of Medicine, Isehara, Japan.
Akira AndohDivision of Gastroenterology, Shiga University of Medical Science, Otsu, Japan.
Hidekazu SuzukiDivision of Gastroenterology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Autonomic imbalance has been reported to correlate with clinical remission in patients with ulcerative colitis (UC). This study evaluated heart rate variability (HRV), a potential digital biomarker, in patients with active UC using a smartwatch that is easy to handle. Methods: Patients with active UC were recruited for this prospective study. The patients' HRV was measured via the Fitbit Inspire2 Results: Nine patients with UC were included. In clinically active disease, SCCAI scores showed a weak inverse relationship with parasympathetic activity, differences of successive R-R pulse intervals (RMSSD) ( Conclusion: Longitudinal nighttime HRV recorded using a smartwatch is associated with disease activity in patients with active UC. In particular, RMSSD and HF, which are indices of the parasympathetic nervous system, have been suggested as potential digital biomarkers for UC.

Indexed as

Autonomic nervous systemHeart rate variabilityInflammatory bowel diseaseUlcerative colitisWearable smart watch

Identifiers

PMID39906590
PMCPMC11793913

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.