Evidence map›Paper›PMID 39906562›Full record

ArticleiScience2025

MORF: Multi-view oblique random forest for hepatotoxicity prediction.

Binsheng Sui, Qingzhuo He, Bowei Yan, Kunhong Liu, Yong Xu, Song He, Xiaochen Bo

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Binsheng SuiDepartment of Digital Media, Xiamen University, Xiamen 361005, China.
Qingzhuo HeWee School of Communication and Information, Nanyang Technological University, Singapore, Singapore.
Bowei YanInstitutes of Biomedical Sciences, Fudan University, Shanghai 200433, China.
Kunhong LiuDepartment of Digital Media, Xiamen University, Xiamen 361005, China.
Yong XuXiamen Key Laboratory of Intelligent Fishery, Xiamen Ocean Vocational College, Xiamen 361100, China.
Song HeInstitute of Health Service and Transfusion Medicine, Beijing 100850, China.
Xiaochen BoInstitute of Health Service and Transfusion Medicine, Beijing 100850, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatotoxicity prediction is significant in drug development, so the experts expect to get effective and reliable references. Based on the consideration that the hepatotoxicity data involve multiple types of features, this paper proposes a multi-view oblique random forest (MORF) for hepatotoxicity prediction by considering each type of feature as an independent view. The Householder transformation is employed to get the inclined cut hyperplane in each view. Two versions of the multi-view oblique decision tree (ODT) algorithms were designed by generating optimal nodes based on selecting proper hyperplanes from different views, named ODT-N and ODT-R. These two types of ODT algorithms serve as the base learners to construct two MORF. Experiments conducted on the hepatotoxicity data provide performance comparisons among different algorithms, and the results confirm that our algorithms can fully utilize the information in different views.

Indexed as

BioinformaticsCancer

Identifiers

PMID39906562
PMCPMC11791245

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.