Evidence map›Paper›PMID 39906420›Full record

ArticleCureus2025

Regression of Bilateral Choroidal Metastases From Primary Lung Carcinoma in Response to Systemic Bevacizumab and Platinum Doublet.

Vaibhav Bhatt, Shweta Parakh, Shrutanjoy Das, Abhijaat Chaturvedi, Suhani Malhotra, Vishali Gupta, Rupesh Agrawal, Gaurav Luthra, Saurabh Luthra

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vaibhav BhattOphthalmology, Drishti Eye Institute, Dehradun, IND.
Shweta ParakhOphthalmology, Drishti Eye Institute, Dehradun, IND.
Shrutanjoy DasOphthalmology, Drishti Eye Institute, Dehradun, IND.
Abhijaat ChaturvediOphthalmology, Drishti Eye Institute, Dehradun, IND.
Suhani MalhotraOphthalmology, Drishti Eye Institute, Dehradun, IND.
Vishali GuptaOphthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, IND.
Rupesh AgrawalOphthalmology, Tan Tock Seng Hospital, Singapore, SGP.
Gaurav LuthraOphthalmology, Drishti Eye Institute, Dehradun, IND.
Saurabh LuthraOphthalmology, Drishti Eye Institute, Dehradun, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 58-year-old male presented with large yellowish choroidal mass lesions with exudative subretinal fluid (SRF) in both eyes. A computed tomography (CT) scan of the thorax revealed a mass lesion in the apical segment of the right upper lobe. Fine needle aspiration cytology (FNAC) of right supraclavicular lymph nodes revealed metastatic mucinous adenocarcinoma. Positron emission tomography-computed tomography scan (PET-CT) showed multiple lymphatic, pulmonary, and skeletal metastases. After six cycles of chemotherapy (platinum doublet and systemic bevacizumab), clinical examination and multimodal imaging showed complete regression of the choroidal lesions. Ours is the first case report of bilateral choroidal metastases from primary pulmonary adenocarcinoma (possibly arising from hazardous occupational exposure in the sericulture industry) that showed complete regression in response to standalone systemic chemotherapy agents, platinum doublet and systemic bevacizumab.

Indexed as

bevacizumabcarcinoma lungchoroidal metastasesmultimodal ophthalmic imagingplatinum based chemotherapy

Identifiers

PMID39906420
PMCPMC11791093

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.