Evidence map›Paper›PMID 39906345›Full record

ArticlePlastic and reconstructive surgery. Global open2025

Implant-based Cryopreserved Autologous Free Nipple Grafting for Breast Reconstruction: The ICEBERG Technique.

Sonia S Patel, Nathan E Lu, Thomas Xia, Brian A Mailey

Abstract read
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sonia S PatelFrom the Saint Louis University School of Medicine, St. Louis, MO.
Nathan E LuFrom the Saint Louis University School of Medicine, St. Louis, MO.
Thomas XiaDivision of Plastic and Reconstructive Surgery, Department of Surgery, Saint Louis University Hospital, St. Louis, MO.
Brian A MaileyDivision of Plastic and Reconstructive Surgery, Department of Surgery, Saint Louis University Hospital, St. Louis, MO.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nipple creation is generally the final step of breast reconstruction. However, patients many times forego this procedure due to reconstructive fatigue. Herein, we describe a technique of harvesting the nipple-areola complex as a full-thickness skin graft during the initial mastectomy with direct-to-implant reconstruction, storing the harvested nipple tissue at -80°C, and then placing the nipple as a skin graft 2 weeks after the initial mastectomy. This method, termed the implant-based cryopreserved autologous free nipple grafting for breast reconstruction technique, serves as a feasible and shorter alternative to traditional procedures. The implant-based cryopreserved autologous free nipple grafting for breast reconstruction technique can, therefore, reduce the longevity of the reconstructive journey for patients.

Identifiers

PMID39906345
PMCPMC11789868

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.