Evidence map›Paper›PMID 39906241›Full record

ArticleHealth science reports2025

Prevalence of Opportunistic Infections and Determinants Among HIV-Positive Patients in Ethiopia: A Systematic Review and Meta-Analysis.

Aleka Aemiro, Abayeneh Girma, Demsew Beletew

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In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

3 authors.

Aleka AemiroDepartment of Biology, College of Natural and Computational Science Mekdela Amba University Tulu Awuliya Ethiopia.ORCID 0000-0001-8634-5111
Abayeneh GirmaDepartment of Biology, College of Natural and Computational Science Mekdela Amba University Tulu Awuliya Ethiopia.ORCID 0000-0001-6155-315X
Demsew BeletewDepartment of Statistics, College of Natural and Computational Science Mekdela Amba University Tulu Awuliya Ethiopia.ORCID 0000-0003-0005-3498

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Opportunistic infections (OIs) associated with HIV are the primary cause of morbidity and mortality among individuals living with HIV/AIDS. Evaluating the extent of OIs at the national level is essential for developing targeted interventions and effective control measures. Therefore, the aim of this study was to evaluate the pooled prevalence and identify the associated factors of OIs among HIV-positive individuals across all age groups. Methods: This systematic review and meta-analysis was conducted following the PRISMA guidelines. It included studies published in English, research articles conducted in Ethiopia, and articles released between 2013 and 2023. A systematic search of articles on the prevalence and determinants of OIs among patients living with HIV in Ethiopia was conducted across four databases (PubMed, ScienceDirect, Scopus, and the Cochrane Library). To evaluate heterogeneity and publication bias, the study employed Cochran's Q, inverse variance (I Results: Of the 207 articles examined, only 26 met the inclusion requirements. The overall prevalence of OIs among HIV-positive patients was 42.71% (95% CI: 36.87-48.56). OIs among HIV-positive individuals were significantly associated with baseline WHO clinical stage II and above (OR: 2.83; 95% CI: 1.93-3.73), khat chewers (OR: 1.94; 95% CI: 1.21-2.66), poor adherence to ART (OR: 2.32; 95% CI: 1.51-3.13), and individuals with an initial CD4 number less than 200 cells/mm Conclusion: Chewing khat, poor adherence, low CD4 count, and WHO stage II and above were found to be predictors of OIs. A constant state of awareness is required for healthcare providers to improve decisions about the proper diagnosis and management of OIs among HIV-positive individuals.

Indexed as

EthiopiaHIVmeta‐analysisopportunistic infectionsprevalencerisk factorssystematic review

Identifiers

PMID39906241
PMCPMC11790600

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