Evidence map›Paper›PMID 39906204›Full record

ReviewMaterials today. Bio2025

Recent advances in iontophoresis-assisted microneedle devices for transdermal biosensing and drug delivery.

Gaobo Wang, Natsuho Moriyama, Soichiro Tottori, Matsuhiko Nishizawa

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gaobo WangDepartment of Biomedical Engineering, School of Medical Engineering, Xinxiang Medical University, Xinxiang, 453003, China.
Natsuho MoriyamaDepartment of Biomedical Engineering, Graduate School of Biomedical Engineering, Tohoku University, 6-6-4 Aramaki Aoba, Aoba-ku, Sendai, 980-8579, Japan.
Soichiro TottoriDepartment of Finemechanics, Graduate School of Engineering, Tohoku University, 6-6-1 Aramaki Aoba, Aoba-ku, Sendai, 980-8579, Japan.
Matsuhiko NishizawaDepartment of Finemechanics, Graduate School of Engineering, Tohoku University, 6-6-1 Aramaki Aoba, Aoba-ku, Sendai, 980-8579, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Integrating advanced manufacturing techniques and nanotechnology with cutting-edge materials has driven significant progress in global healthcare. Microneedles, recognized for their minimally invasive approach to transdermal sensing and drug delivery, achieve enhanced functionality when combined with iontophoresis. Iontophoresis-assisted microneedles have emerged as an innovative solution, enabling real-time biosensing and precise drug delivery within closed-loop systems. These integrated platforms represent a major advancement in personalized medicine, allowing dynamic therapeutic adjustments based on continuous feedback. This review highlights the latest developments in iontophoresis-assisted microneedles for transdermal biosensing, drug delivery, and closed-loop applications. It delves into the mechanisms of iontophoresis, assesses its advantages and limitations, and explores future directions for these transformative technologies.

Indexed as

Closed-loop systemDrug deliveryIontophoresisMicroneedleTransdermal sensing

Identifiers

PMID39906204
PMCPMC11791360

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.