Evidence map›Paper›PMID 39906142›Full record

ArticleNanoscale advances2025

MPI performance of magnetic nanoparticles depends on matrix composition and temperature: implications for

Marzieh Salimi, Wenshen Wang, Stéphane Roux, Gautier Laurent, Rana Bazzi, Patrick Goodwill, Guanshu Liu, Jeff W M Bulte

Abstract read
In one paragraph

Article in Nanoscale advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marzieh SalimiRussell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, The Johns Hopkins University Baltimore Maryland USA jwmbulte@mri.jhu.edu.ORCID https://orcid.org/0000-0002-8426-5975
Wenshen WangRussell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, The Johns Hopkins University Baltimore Maryland USA jwmbulte@mri.jhu.edu.
Stéphane RouxUniversité de Franche-Comté, CNRS, Chrono-Environnement F-25000 Besançon France.ORCID https://orcid.org/0000-0002-5198-1916
Gautier LaurentUniversité de Franche-Comté, CNRS, Chrono-Environnement F-25000 Besançon France.ORCID https://orcid.org/0000-0002-8544-1379
Rana BazziUniversité de Franche-Comté, CNRS, Chrono-Environnement F-25000 Besançon France.ORCID https://orcid.org/0000-0001-7274-6694
Patrick GoodwillMagnetic Insight Inc. Alameda CA USA.ORCID https://orcid.org/0000-0003-4240-1956
Guanshu LiuRussell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, The Johns Hopkins University Baltimore Maryland USA jwmbulte@mri.jhu.edu.
Jeff W M BulteRussell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, The Johns Hopkins University Baltimore Maryland USA jwmbulte@mri.jhu.edu.ORCID https://orcid.org/0000-0003-1202-1610

Funding

Precision magnetic hyperthermia by integrating magnetic particle imagingR01CA257557 · NCI · JOHNS HOPKINS UNIVERSITY · PI BULTE, JEFF W., IVKOV, ROBERT · 2021 to 2025
$3.2M
Development of a prototype clinical theranostic platform combining Magnetic Particle Imaging (MPI) and Magnetic Fluid Hyperthermia (MFH) for the treatment of brain tumorsR44CA285064 · NCI · MAGNETIC INSIGHT, INC. · PI GOODWILL, PATRICK · 2023 to 2024
$2.0M
MPI/MRI bimodal imaging for non-invasive tracking of extracellular vesicles targeted to infarcted myocardiumR33HL161756 · NHLBI · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI LIU, GUANSHU · 2022 to 2023
$966k
Non-Invasive Tracking of Genome-Corrected iPS cells in ALSUH3EB028904 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI BULTE, JEFF W. · 2021 to 2022
$950k
Magnetic Particle Imaging ScannerS10OD026740 · OD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI BULTE, JEFF W. · 2019 to 2019
$600k
Non-Invasive Tracking of Genome-Corrected iPS cells in ALSUH2EB028904 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI BULTE, JEFF W. · 2019 to 2020
$482k
NCI NIH HHS R01 CA257557NCI NIH HHS R44 CA285064NHLBI NIH HHS R33 HL161756NIBIB NIH HHS UH2 EB028904NIBIB NIH HHS UH3 EB028904NIH HHS S10 OD026740
6 · The paper itself

Abstract

One of the hallmark advantages of magnetic particle imaging (MPI) is the linear relationship between MPI signal and the concentration of magnetic nanoparticles (MNPs), allowing absolute tracer quantification. However, intrinsic tissue matrix parameters may affect the MPI signal, often unknown

Identifiers

PMID39906142
PMCPMC11789940

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.