Evidence map›Paper›PMID 39905988›Full record

ReviewJournal of medical virology2025

Bilayer or Not: Revisiting the Structural Nature of HBV Subviral Particles.

Haitao Liu, Sonal Garg, Jianming Hu, Joseph Che-Yen Wang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of medical virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Haitao LiuDepartment of Microbiology and Immunology, Penn State College of Medicine, Hershey, Pennsylvania, USA.ORCID 0000-0002-6263-1508
Sonal GargDepartment of Microbiology and Immunology, Penn State College of Medicine, Hershey, Pennsylvania, USA.ORCID 0000-0002-0004-7939
Jianming HuDepartment of Microbiology and Immunology, Penn State College of Medicine, Hershey, Pennsylvania, USA.ORCID 0000-0002-3967-2133
Joseph Che-Yen WangDepartment of Microbiology and Immunology, Penn State College of Medicine, Hershey, Pennsylvania, USA.ORCID 0000-0001-6580-3531

Funding

Mechanisms of Hepadnavirus Assembly and ReplicationR37AI043453 · NIAID · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI Jianming Hu · 2018 to 2026
$3.8M
Structural characterization of native HBV capsids and virions from human cellsR01AI173104 · NIAID · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI Joseph Che-Yen Wang · 2023 to 2026
$2.8M
NIAID NIH HHS R01 AI173104NIAID NIH HHS R37 AI043453This study was supported by National Institute of Allergy and Infectious Diseases R01AI173104(J.C-Y.W.)This study was supported by National Institute of Allergy and Infectious Diseases R37AI043453(J.H.)
6 · The paper itself

Abstract

Hepatitis B virus (HBV) subviral particles (SVPs) are primarily stabilized by protein-protein interactions, with discrete lipid patches playing a supporting role, rather than forming a conventional lipid bilayer, challenging classical assumptions about viral membrane architecture.

Indexed as

Hepatitis B virusLipid BilayersVirionHumansLipid Bilayers

Identifiers

PMID39905988
PMCPMC11795223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.