Evidence map›Paper›PMID 39905823›Full record

ArticlePsychological medicine2025

Altered food liking in depression is driven by macronutrient composition.

Lilly Thurn, Corinna Schulz, Diba Borgmann, Johannes Klaus, Sabine Ellinger, Martin Walter, Nils B Kroemer

Abstract read
In one paragraph

Article in Psychological medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lilly ThurnSection of Medical Psychology, Department of Psychiatry & Psychotherapy, Faculty of Medicine, University of Bonn, Bonn, Germany.ORCID 0009-0004-8947-3337
Corinna SchulzSection of Medical Psychology, Department of Psychiatry & Psychotherapy, Faculty of Medicine, University of Bonn, Bonn, Germany.ORCID 0000-0001-9885-655X
Diba BorgmannNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.ORCID 0009-0003-8507-7946
Johannes KlausDepartment of Psychiatry & Psychotherapy, Tübingen Center for Mental Health, University of Tübingen, Tübingen, Germany.ORCID 0000-0003-0956-1755
Sabine EllingerInstitute of Nutritional and Food Sciences, Human Nutrition, University of Bonn, Bonn, Germany.ORCID 0000-0002-9988-9406
Martin WalterDepartment of Psychiatry & Psychotherapy, Tübingen Center for Mental Health, University of Tübingen, Tübingen, Germany.ORCID 0000-0001-7857-4483
Nils B KroemerSection of Medical Psychology, Department of Psychiatry & Psychotherapy, Faculty of Medicine, University of Bonn, Bonn, Germany.ORCID 0000-0002-9552-3781

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Major depressive disorder (MDD) is characterized by changes in appetite and body weight as well as blunted reward sensitivity (‘anhedonia’). However, it is not well understood which mechanisms are driving changes in reward sensitivity, specifically regarding food. Here, we used a sample of 117 participants (54 patients with MDD and 63 healthy control participants [HCPs]) who completed a food cue reactivity task with ratings of wanting and liking for 60 food and 20 non-food items. To evaluate which components of the food may contribute to altered ratings in depression, we tested for associations with macronutrients of the depicted items. In line with previous studies, we found reduced ratings of food wanting (

Indexed as

AnhedoniaFood PreferencesMajor Depressive DisorderNutrientsRewardAdultDietary CarbohydratesDietary FatsFemaleHumansMaleMiddle AgedYoung AdultDietary CarbohydratesDietary FatsNutrientsAppetitecarbohydratesfatfood rewardmajor depressive disorderprotein

Identifiers

PMID39905823
PMCPMC12017361

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.