Evidence map›Paper›PMID 39905749›Full record

ArticleJournal of diabetes investigation2025

Validation using item response theory, and assessment of sensitivity to change of the Hypoglycemia Awareness Questionnaire in patients with type 2 diabetes treated with insulin.

Julieth Patricia García-Lugo, Ana Julia Carrillo Algarra, Fabio Alexander Sierra-Matamoros, Sandra Milena Hernández-Zambrano, Diana Cristina Henao-Carrillo

Abstract readValidation Study
In one paragraph

Article in Journal of diabetes investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julieth Patricia García-LugoFundación Universitaria de Ciencias de la Salud (FUCS), Bogotá, Colombia.
Ana Julia Carrillo AlgarraSchool of Nursing, Fundación Universitaria de Ciencias de la Salud (FUCS), Bogotá, Colombia.
Fabio Alexander Sierra-MatamorosFundación Universitaria de Ciencias de la Salud (FUCS), Bogotá, Colombia.
Sandra Milena Hernández-ZambranoSchool of Nursing, Fundación Universitaria de Ciencias de la Salud (FUCS), Bogotá, Colombia.
Diana Cristina Henao-CarrilloEndocrinology Unit, San Ignacio Hospital, Pontificia Universidad Javeriana, Bogotá, Colombia.ORCID https://orcid.org/0000-0002-1353-148X

Funding

Fundación Universitaria de Ciencias de la Salud 2019
6 · The paper itself

Abstract

AIMS/

introductionIt is important to develop valid tools to evaluate hypoglycemia perception such as the Hypoglycemia Awareness Questionnaire (HypoA-Q) in patients with Type 2 Diabetes (T2D). The aim of the study is to validate the HypoA-Q in patients with T2D treated with insulin using item response theory. MATERIALS AND

methodsIndividuals with T2D treated with insulin were included by non-random convenience sampling. A partial credit model was used for validation using item response theory, infit, and outfit statistics were calculated, person-item map and item characteristic curves were plotted, and differential item functioning was assessed.

resultsThe study included 502 participants, the mean age at diagnosis of diabetes was 47.8 ± 13.9 years, the median time with the diagnosis was 15 years (IQR: 9-22), and the mean HbA1c 71 ± 27.3 mmol/mL (8.6 ± 2.5%), 48.6% had Glomerular Filtration Rate >60 mL/min/min

conclusionsThe HypoA-Q is a valid measure for assessing hypoglycemia awareness in insulin-treated T2D patients because it has items that fit the measurement process, measures a wide range of awareness, and is free of biases related to gender, age, treatment, and duration of diabetes.

Indexed as

AwarenessDiabetes Mellitus, Type 2HypoglycemiaHypoglycemic AgentsInsulinAdultAgedFemaleHumansMaleMiddle AgedPrognosisSurveys and QuestionnairesHypoglycemic AgentsInsulinHypoA‐Q questionnaireType 2 DiabetesUnawareness hypoglycemia

Identifiers

PMID39905749
PMCPMC12057381

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.