Evidence map›Paper›PMID 39905658›Full record

ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2025

Long-term bowel function following delayed coloanal anastomosis: Analysis of a multicentric cohort study (GRECCAR).

Maxime K Collard, Jean-Jacques Tuech, Charles Sabbagh, Amine Souadka, Jérome Loriau, Eric Rullier, Frédéric Marchal, Adeline Germain, Stéphane Benoist, Jean-Luc Faucheron and 23 more

Abstract readMulticenter Study
In one paragraph

Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Long-term bowel function following delayed coloanal anastomosis: Analysis of a multicentric cohort study (GRECCAR).Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Maxime K CollardDepartment of Colorectal Surgery, Hôpital Saint-Antoine, Assistance Publique Hôpitaux de Paris, Sorbonne University, Paris, France.ORCID https://orcid.org/0000-0002-7882-6860
Jean-Jacques TuechDepartment of General and Digestive Surgery, Hôpital Charles Nicole, Rouen, France.ORCID https://orcid.org/0000-0001-9436-8938
Charles SabbaghDepartment of General and Digestive Surgery, Hôpital d'Amiens, Amiens, France.ORCID https://orcid.org/0000-0001-7525-0627
Amine SouadkaDepartment of General and Digestive Surgery, National Institute of Oncology, Rabat, Morocco.ORCID https://orcid.org/0000-0002-1091-9446
Jérome LoriauDepartment of General and Digestive Surgery, Hôpital Saint-Joseph, Paris, France.ORCID https://orcid.org/0000-0002-7310-4244
Eric RullierDepartment of General and Digestive Surgery, Saint André Hospital, Bordeaux, France.
Frédéric MarchalDepartment of General and Digestive Surgery, Institut de cancérologie de Lorraine, Vandoeuvre-les-Nancy, France.
Adeline GermainDepartment of General and Digestive Surgery, Hôpital Universitaire de Nancy, Nancy, France.ORCID https://orcid.org/0000-0001-8076-3742
Stéphane BenoistDepartment of General and Digestive Surgery, Hôpital du Kremlin-Bicêtre, Kremlin-Bicêtre, France.
Jean-Luc FaucheronDepartment of Colorectal Surgery, Hôpital Unversitaire de Grenoble, La Tronche, France.ORCID https://orcid.org/0000-0002-0837-2277
Gilles ManceauDepartment of General and Digestive Surgery, Hôpital Européen Georges Pompidou, Paris, France.ORCID https://orcid.org/0000-0002-0783-8688
Anne DuboisDepartment of General and Digestive Surgery, CHU Clermont-Ferrand Site Estaing, Clermont-Ferrand, France.
Anaïs LaforestDepartment of General and Digestive Surgery, Institut Monsouris, Paris, France.
Isabelle SourrouilleGustave Roussy, Département d'Anesthésie, Chirurgie et Interventionnel, Villejuif, France.
Aurore ProtatDepartment of General and Digestive Surgery, Hôpital Huriez, Lille, France.
Diane MègeDepartment of General and Digestive Surgery, Hôpital de la Timone, Marseille, France.ORCID https://orcid.org/0000-0002-7556-6362
Zaher LakkisDepartment of Digestive Surgery, University Hospital of Besancon, Besancon, France.ORCID https://orcid.org/0000-0002-2608-5896
Michel PrudhommeDepartment of General and Digestive Surgery, Hôpital Universitaire de Nîmes, Nîmes, France.
Simon DerieuxDepartment of General and Digestive Surgery, Groupe Hospitalier Diaconesses - Croix Saint Simon, Paris, France.
Mehdi OuaissiDepartment of General and Digestive Surgery, Hôpital Trousseau - CHRU Hôpitaux de Tours, Chambray-lès-Tours, France.
Aurélien VenaraDepartment of General and Digestive Surgery, Hôpital Universitaire d'Angers, Angers, France.
Cécile BrigandDepartment of General and Digestive Surgery, Hôpital de Hautepierre - Hôpitaux Universitaires, Strasbourg, France.
Bernard LelongDepartment of General and Digestive Surgery, Institut Paoli-Calmettes, Marseille, France.
Karine PautratDepartment of General and Digestive Surgery, Hôpital Lariboisière, Paris, France.
Leon MaggioriDepartment of General and Digestive Surgery, Hôpital Lariboisière, Paris, France.ORCID https://orcid.org/0000-0002-9957-9897
Gil LebretonDepartment of General and Digestive Surgery, CHU côte de Nâcre, Caen, France.
Philippe RouanetDepartment of General and Digestive Surgery, Institut du Cancer de Montpellier, Montpellier, France.
Marc PocardDepartment of General and Digestive Surgery, Hôpital Pitié-Salpêtrière, Paris, France.ORCID https://orcid.org/0000-0002-4793-0008
Emilie DuchalaisDepartment of General and Digestive Surgery, Centre Hospitalier Universitaire de Nantes, Nantes, France.ORCID https://orcid.org/0000-0003-3654-2963
Quentin DenostDepartment of General and Digestive Surgery, Bordeaux Colorectal Institute, Bordeaux, France.ORCID https://orcid.org/0000-0003-3088-5244
Yann ParcDepartment of Colorectal Surgery, Hôpital Saint-Antoine, Assistance Publique Hôpitaux de Paris, Sorbonne University, Paris, France.
Jérémie H LefevreDepartment of Colorectal Surgery, Hôpital Saint-Antoine, Assistance Publique Hôpitaux de Paris, Sorbonne University, Paris, France.ORCID https://orcid.org/0000-0001-7601-7464
GRECCAR Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimAlteration of bowel function after delayed coloanal anastomosis (DCAA) might be a limitation to its utilization. Our aim was to assess the long-term bowel function of DCAA in a large multicentric cohort.

methodAll patients who underwent DCAA interventions at 29 GRECCAR-affiliated hospitals between 2010 and 2021 were retrospectively included. Low anterior resection syndrome (LARS) score or confection of a stoma due to poor bowel function was assessed in eligible patients. Good bowel function was defined by the preservation of bowel continuity with no LARS or a minor LARS.

resultsAmong the 385 eligible patients to assess long-term bowel continuity, 63% (n = 243) responded to the questionnaire or had a definitive stoma because of poor bowel function. After a median follow-up of 32 months, good bowel function was reported by 60% (n = 146) of patients (with no LARS 36% and minor LARS 24%), whereas 40% of patients (n = 146) had a poor bowel function including major LARS (36%) and definitive stoma due to poor bowel function (4%). No variables tested were predictive of a poor bowel function after DCAA, including a history of pelvic radiotherapy (P = 0.722), salvage DCAA after failure of a previous anastomosis (P = 0.755), presence of a diverting stoma (P = 0.556), occurrence of an anastomotic leakage (P = 0.416) and time interval from the DCAA to the bowel function assessment (P = 0.350).

conclusionsNo LARS or minor LARS was reached for 60% of patients after DCAA. Less than 5% of patients received a definitive stoma due to a poor bowel function.

Indexed as

Anal CanalAnastomosis, SurgicalColonPostoperative ComplicationsAdultAgedAged, 80 and overDefecationFemaleHumansMaleMiddle AgedProctectomyRetrospective StudiesSurgical StomasTime Factorsanterior resection syndromecoloanal anastomosisLARSrectal cancer

Identifiers

PMID39905658
PMCPMC11794976

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.