Evidence map›Paper›PMID 39905593›Full record

SynthesisPsychophysiology2025

Diminished Interoceptive Accuracy in Attention-Deficit/Hyperactivity Disorder: A Systematic Review.

Alisha M Bruton, Laura Levy, Navdeep Kaur Rai, Dana Dharmakaya Colgan, Jeanette M Johnstone

Abstract readSystematic Review
In one paragraph

Synthesis in Psychophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alisha M BrutonCenter for Mental Health Innovation, Department of Psychiatry, Oregon Health & Science University, Portland, Oregon, USA.ORCID 0000-0002-5929-3149
Laura LevySchool of Medicine, Oregon Health & Science University, Portland, Oregon, USA.
Navdeep Kaur RaiUniversity of Western States, Portland, Oregon, USA.
Dana Dharmakaya ColganNational University of Natural Medicine, Portland, Oregon, USA.
Jeanette M JohnstoneCenter for Mental Health Innovation, Department of Psychiatry, Oregon Health & Science University, Portland, Oregon, USA.

Funding

CAM Research Training in Neuroscience &StressT32AT002688 · NCCIH · OREGON HEALTH & SCIENCE UNIVERSITY · PI OKEN, BARRY S, SOUMYANATH, AMALA · 2005 to 2025
$7.2M
Building Research across Interdisciplinary Gaps (BRIDG) R90 Training Program - Administrative SupplementR90AT008924 · NCCIH · NATIONAL UNIVERSITY OF NATURAL MEDICINE · PI BRADLEY, RYAN D, ZWICKEY, HEATHER LEA · 2015 to 2025
$5.2M
Mindful Body Awareness Training as an Adjunct to Medication Assisted Treatment for Opioid Use Disorder: An ancillary studyR01AT010742 · NCCIH · UNIVERSITY OF WASHINGTON · PI MERRILL, JOSEPH O, PRICE, CYNTHIA J · 2019 to 2022
$2.4M
Optimizing Research Methodology in a Multinutrient Study of Racially and Ethnically Diverse Children with ADHD and Emotional DysregulationK23AT012068 · NCCIH · OREGON HEALTH & SCIENCE UNIVERSITY · PI JOHNSTONE, JEANETTE M · 2022 to 2025
$700k
NCCIH NIH HHS 5R90AT008924-08NCCIH NIH HHS K23 AT012068NCCIH NIH HHS K23 AT012068-01NCCIH NIH HHS R01 AT010742NCCIH NIH HHS R90 AT008924NCCIH NIH HHS T32 AT002688NCCIH NIH HHS T32 #AT002688NINDS NIH HHS R01AT010742-01
6 · The paper itself

Abstract

Interoception is the perception of one's internal physiological state. Altered interoception may play a role in the pathogenesis of attention-deficit/hyperactivity disorder (ADHD). We reviewed the literature on interoception and ADHD symptoms (inattention, hyperactivity/impulsivity, executive function, emotional dysregulation) in individuals with and without the disorder. Studies included assessments of interoception and ADHD symptoms in (1) individuals with/without diagnoses of ADHD or (2) the general population. Interoception assessments included objective measures (heartbeat-tracking test) and self-report questionnaires. The literature search included the PubMed/MEDLINE, PsychINFO, CINAHL and Scopus databases. A protocol was prospectively registered in the PROSPERO database (CRD #42022351726); the PRISMA guidelines directed reporting. The Newcastle-Ottawa scale was adapted to evaluate study quality. Of 636 articles identified, 17 articles (based on 18 studies) met inclusion criteria. Five studies compared interoception in participants with/without ADHD, and three found that interoception was reduced in participants with ADHD. One study compared interoception between presentations of ADHD, finding no differences. Twelve studies assessed the association of ADHD symptoms and interoception in the general population. Overall, results suggested that interoception is reduced in individuals who reported higher symptoms of inattention, hyperactivity, impulsivity, emotional dysregulation, and executive dysfunction. Studies were of moderate quality; issues included small sample sizes and inadequate reporting. Individuals with ADHD may have decreased interoception compared to individuals without. Interoception is negatively associated with ADHD symptoms in the general population. Interventions focused on improving interoceptive abilities may provide an avenue for ADHD treatment. Future work should consider the role of culture in interoception.

Indexed as

Attention Deficit Disorder with HyperactivityInteroceptionExecutive FunctionHumans

Identifiers

PMID39905593
PMCPMC11842156

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.