Evidence map›Paper›PMID 39905517›Full record

ArticleNutrition journal2025

Burden of diseases attributable to excess body weight in 204 countries and territories, 1990-2019.

Saeid Safiri, Jessica A Grieger, Amir Ghaffari Jolfayi, Seyed Ehsan Mousavi, Seyed Aria Nejadghaderi, Asra Fazlollahi, Mark J M Sullman, Nahid Karamzad, Fikrettin Sahin, Kuljit Singh and 2 more

Abstract read
In one paragraph

Article in Nutrition journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. NR4A1-Driven Granulosa Cell Ferroptosis Contributes to Obesity-Related Ovarian Dysfunction and Metformin-Mediated Ovarian Protection.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Unmasking Hormonal Mechanisms of Hypertension in Obesity.JACC. Basic to translational science · 2026
    Article
  7. Article
  8. Anti-Obesity Activity of GiantInternational journal of molecular sciences · 2026
    Article
  9. Weight Trajectory Impacts Risk for 10 Distinct Cardiometabolic Diseases.The Journal of clinical endocrinology and metabolism · 2025
    Article
  10. Unmasking Hormonal Mechanisms of Hypertension in Obesity.medRxiv : the preprint server for health sciences · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Saeid SafiriResearch Center for Integrative Medicine in Aging, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran. safiris@tbzmed.ac.ir.
Jessica A GriegerAdelaide Medical School, University of Adelaide, Adelaide, SA, Australia.
Amir Ghaffari JolfayiCardiovascular Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
Seyed Ehsan MousaviNeurosciences Research Center, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Seyed Aria NejadghaderiHIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.
Asra FazlollahiSocial Determinants of Health Research Center, Department of Community Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Mark J M SullmanDepartment of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus.
Nahid KaramzadDepartment of Persian Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Fikrettin SahinDepartment of Genetics and Bioengineering, Yeditepe University, Istanbul, Turkey.
Kuljit SinghDepartment of Medicine, Griffith University, Southport, QLD, Australia.
Gary S CollinsCentre for Statistics in Medicine, NDORMS, Botnar Research Centre, University of Oxford, Oxford, UK.
Ali-Asghar KolahiSocial Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. a.kolahi@sbmu.ac.ir.ORCID http://orcid.org/0000-0003-0178-3732

Funding

Shahid Beheshti University of Medical Sciences 43005963
6 · The paper itself

Abstract

backgroundTo investigate the global, regional, and national burden of the diseases attributable to excess body weight (EBW) from 1990 to 2019, stratified by age, sex, underlying cause, and sociodemographic index (SDI).

methodsUsing the Comparative Risk Assessment approach of the Global Burden of Disease (GBD) study 2019, the burden of diseases attributable to EBW was reported for the period from 1990 to 2019. For adults, EBW was defined as a body mass index (BMI) exceeding 25 kg/m

resultsIn 2019, there were an estimated 5.0 million deaths (95% UI: 3.2-7.1) and 160.3 million DALYs (106.0-218.9) attributable to EBW worldwide. The age-standardised DALY rate attributable to EBW increased by 18.0% (2.2-42.3) from 1990 to 2019, with notable regional variations. Southeast Asia and South Asia exhibited the highest age-standardised DALY rates. Conversely, the age-standardised death rate due to EBW showed no significant change, with an increase of 4.9% (-7.3 to 24.6) over the same period. Significant regional variations were again observed, particularly in Southeast Asia and South Asia, which recorded the highest age-standardised death rates. Moreover, a non-linear association was observed between the SDI and the regional age-standardised DALY rate of diseases attributable to EBW.

conclusionsThe global burden of EBW has increased over the past three decades. This trend aligns with socio-demographic indices and is influenced by the physical activity levels and dietary habits of these populations.

Indexed as

Cost of IllnessGlobal Burden of DiseaseObesityOverweightAdolescentAdultAgedBody Mass IndexChildChild, PreschoolDisability-Adjusted Life YearsFemaleGlobal HealthHumansInfantMaleDeathDisability-adjusted life-yearIncidenceMortalityObesityOverweightPrevalence

Identifiers

PMID39905517
PMCPMC11796013

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.