Evidence map›Paper›PMID 39905487›Full record

ArticleJournal of nanobiotechnology2025

Theranostic nanoemulsions suppress macrophage-mediated acute inflammation in rats.

Riddhi Vichare, Yalcin Kulahci, Rebecca McCallin, Fatih Zor, Fatma Nurefsan Selek, Lu Liu, Caitlin Crelli, Anneliese Troidle, Michele Herneisey, James M Nichols and 3 more

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. A self-assembled and HTheranostics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Riddhi VichareSchool of Pharmacy and Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA, USA.
Yalcin KulahciDepartment of Surgery, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Rebecca McCallinSchool of Pharmacy and Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA, USA.
Fatih ZorDepartment of Surgery, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Fatma Nurefsan SelekDepartment of Surgery, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Lu LiuSchool of Pharmacy and Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA, USA.
Caitlin CrelliSchool of Pharmacy and Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA, USA.
Anneliese TroidleSchool of Pharmacy and Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA, USA.
Michele HerneiseySchool of Pharmacy and Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA, USA.
James M NicholsDepartment of Symptom Research, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Andrew J ShepherdDepartment of Symptom Research, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Vijay S GorantlaDepartment of Surgery, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Jelena M JanjicSchool of Pharmacy and Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA, USA. janjicj@duq.edu.

Funding

AFMSA FA8650-20-C-6215Congressionally Directed Medical Research Programs W81XWH-20-1-0730
6 · The paper itself

Abstract

In inflammatory diseases or following an injury, dysregulated inflammation is a common driver of pain and tissue damage. Macrophages are immune cells that contribute to the initiation, maintenance, and resolution of inflammation due to their phenotypic plasticity in response to signals from inflammatory microenvironments. Macrophages infiltrate and polarize toward a pro-inflammatory phenotype (M

Indexed as

Anti-Inflammatory AgentsCurcuminInflammationMacrophagesNanoparticlesTheranostic NanomedicineAnimalsCytokinesEmulsionsMaleRatsRats, Sprague-DawleyRAW 264.7 CellsAnti-Inflammatory AgentsCurcuminCytokinesEmulsionsCurcuminInflammationMacrophagesNanoemulsionsTheranostic

Identifiers

PMID39905487
PMCPMC11792706

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.