Evidence map›Paper›PMID 39905478›Full record

ArticleReproductive biology and endocrinology : RB&E2025

Association between sleep during pregnancy and birth outcomes: a prospective cohort study.

Libing Huang, Huanjun Chen, Fuhui Yao, Zhonghan Sun, Shijiao Yan, Yuwei Lai, Chuanzhu Lv, Xiong-Fei Pan, Rixing Wang, Xingyue Song

Abstract read
In one paragraph

Article in Reproductive biology and endocrinology : RB&E, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Libing Huang *Department of Emergency, Zhanjiang Central People's Hospital, Zhanjiang, 524000, China.
Huanjun Chen *Danzhou Center for Disease Control and Prevention, Danzhou, 571700, Hainan, China.
Fuhui YaoDepartment of Emergency, Hainan Clinical Research Center for Acute and Critical Diseases, The Second Affiliated Hospital of Hainan Medical University, Haikou, 570100, China.
Zhonghan SunHuman Phenome Institute, Fudan University, Shanghai, 200000, China.
Shijiao YanSchool of Public Health, Hainan Medical University, Haikou, 570100, Hainan, China.
Yuwei LaiDepartment of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China.
Chuanzhu LvEmergency Medicine Center, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China.
Xiong-Fei PanSection of Epidemiology and Population Health, Department of Gynecology and Obstetrics, Ministry of Education Key Laboratory of Birth Defects and Related Diseases of Women and Children & National Medical Products Administration Key Laboratory for Technical Research on Drug Products In Vitro and In Vivo Correlation, West China Second University Hospital, Sichuan University, Chengdu, 610041, China. pxiongfei@scu.edu.cn.
Rixing WangDepartment of Emergency, Hainan Clinical Research Center for Acute and Critical Diseases, The Second Affiliated Hospital of Hainan Medical University, Haikou, 570100, China. wangrixing903@126.com.
Xingyue SongDepartment of Emergency, Hainan Clinical Research Center for Acute and Critical Diseases, The Second Affiliated Hospital of Hainan Medical University, Haikou, 570100, China. songxingyue2015@163.com.

Funding

Science and Technology Department of Hainan Province 821RC557Science and Technology Department of Hainan Province 822RC845Science and Technology Department of Hainan Province LCYX202205
6 · The paper itself

Abstract

objectiveA prospective cohort study was conducted to investigate sleep status during the early and second trimester of pregnancy in pregnant women on adverse birth outcome, such as preterm birth, low birth weight and small for gestational age.

methodsMultivariable logistic regression models were used to analyze the association of sleep status during the early and second trimester of pregnancy with adverse birth outcomes and generated the odds ratio and 95% confidence interval.

results5,418 pregnant women were included in the analysis. In the multivariable model, compared with 7.1-8 h/night, sleep ≤ 7 h/night during second trimester increases the risk of preterm birth (OR: 1.43, 95% CI: 1.12,1.85), and the risk of preterm birth was decreased in pregnant women who slept > 9 h/night (OR: 0.79, 95% CI: 0.53,0.93). Sleep quality, and sleep changes in the early and second trimesters, and sleep duration in the early pregnancy were not statistically associated with preterm birth, low birth weight and small for gestational age.

conclusionsShort sleep duration during pregnancy is associated with a higher risk of preterm birth and longer sleep duration at night is associated with a lower risk of preterm birth, but the latter needs further verification. Sleep status during pregnancy was not associated with low birth weight and small for gestational age. In order to reduce risk of adverse birth outcomes, sleep problems in pregnant women should be strengthened during pregnancy care. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Pregnancy OutcomePremature BirthSleepAdultCohort StudiesFemaleHumansInfant, Low Birth WeightInfant, NewbornInfant, Small for Gestational AgePregnancyPregnancy Trimester, SecondProspective StudiesSleep QualityYoung AdultAdverse birth outcomesCohort studySleep durationSleep quality

Identifiers

PMID39905478
PMCPMC11792202

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.