ArticleBMC psychiatry2025
Association among financial toxicity, depression and fear of cancer recurrence in young breast cancer patient-family caregiver dyads: an actor-partner interdependence mediation model.
Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison of the effects of cognitive-supportive-relaxation multimodal psychosocial intervention on fear of cancer recurrence and psychological resilience in breast cancer patients: a network meta-analysis based on randomized controlled trials.Frontiers in oncology · 2026Pooled it
- Financial hardship in adolescent and young adult cancer survivors and adult survivors of childhood cancers.Journal of cancer survivorship : research and practice · 2026Review
- Cross-Cultural Adaptation and Psychometric Validation of the Cancer Survivors' Unmet Needs Measure (CaSUN) in Russian- and Kazakh-Speaking Cancer Survivors in Kazakhstan.Healthcare (Basel, Switzerland) · 2026Article
- The influence of family resilience and benefit finding on the financial toxicity of primary caregivers of patients with advanced cancer: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Fear of Cancer Recurrence and Coping in Young Breast Cancer Survivors: A Secondary Analysis.Cancer medicine · 2026Observational
- Interpretable machine learning for prognostic prediction in young women with triple-negative invasive ductal breast cancer: a Boruta-SHAP integrated approach.Gland surgery · 2026Article
- Relationship between social capital and depression among middle-aged and older patients with breast cancer in China: mediating effect of posttraumatic growth.BMC psychology · 2026Article
- Adolescent and young adult cancer survivor experiences of financial toxicity: a scoping review.Journal of cancer survivorship : research and practice · 2026Review
- Dyadic family hardiness and coping styles on fear of cancer recurrence in adolescent malignant bone tumor patients and caregivers.Scientific reports · 2026Article
- Factors influencing anxiety and depression among patients with digestive tract subepithelial lesions.World journal of psychiatry · 2026Article
- The Developmental Trajectory of Learned Helplessness in Breast Cancer Chemotherapy Patients: A Longitudinal Study Based on Latent Growth Models.Patient preference and adherence · 2026Article
- The association between fear of disease progression and financial toxicity in patients with chronic osteomyelitis: a cross-sectional study.Frontiers in psychology · 2026Article
- Early identification and prevention of depressive symptoms in breast cancer patients.World journal of clinical oncology · 2025Article
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7 authors.
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Abstract
purposeThis study aimed to investigate the depression situation and the mediating role of fear of cancer recurrence (FCR) in the relationship between financial toxicity and depression in young breast cancer (BC) patient-family caregiver dyads.
methodsA total of 196 young BC patient-family caregiver dyads at four hospitals in China were investigated. The Comprehensive scores for financial toxicity based on patient-reported outcome measures, the Hospital Anxiety and Depression Scale, and the FCR Inventory Short Form were assessed. The actor-partner interdependence mediation model using structural equation modelling in AMOS software was applied to examine the direct and indirect effects.
resultsIn this study, there were 196 pairs of patients and family caregivers. The findings indicated a significant correlation between financial toxicity and FCR in both young BC patients and their family caregivers. Two significant partner effects were observed: the family caregiver's financial toxicity significantly influenced the patient's FCR (β=-0.450, P < 0.001), and the patient's FCR influenced the family caregiver's depression (β = 0.570, P < 0.001). Furthermore, financial toxicity in both young BC patients and family caregivers markedly affected both the actor and partner effects on dyadic depression, primarily through the patients' FCR.
conclusionsDepression in young BC patients was affected not only by themselves but also by their family caregivers. Emphasis should be placed on the interplay between financial toxicity and FCR of patients and family caregivers, with the aim of improving depression for young BC patients. CLINICAL IMPLICATIONS: The study emphasized the importance of addressing the experiences of both patient and family caregivers in clinical interventions. By demonstrating how financial toxicity and FCR are interlinked with depression in both parties, the study supports the development of we offer empirical support for developing comprehensive intervention strategies to alleviate mental distress and enhance mental health for patients and family caregivers.
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