Evidence map›Paper›PMID 39905185›Full record

ArticleScientific reports2025

A novel combination of treatments for acute anterior disc displacement without reduction of temporomandibular joint.

Zhi-Qiang Song, Chen-Xi Li, Zhong-Cheng Gong

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhi-Qiang Song *Department of Oral and Maxillofacial Oncology & Surgery, School / Hospital of Stomatology, The First Affiliated Hospital of Xinjiang Medical University, No. 137 Liyushan South Road, Urumqi, 830054, China.
Chen-Xi Li *Department of Oral and Maxillofacial Oncology & Surgery, School / Hospital of Stomatology, The First Affiliated Hospital of Xinjiang Medical University, No. 137 Liyushan South Road, Urumqi, 830054, China. lichenxiuke@gmail.com.
Zhong-Cheng GongDepartment of Oral and Maxillofacial Oncology & Surgery, School / Hospital of Stomatology, The First Affiliated Hospital of Xinjiang Medical University, No. 137 Liyushan South Road, Urumqi, 830054, China. gzc740904@xjmu.edu.cn.

Funding

National Natural Science Foundation of China 82160189Natural Science Foundation of Xinjiang Uygur Autonomous Region 2023D01D14Scientific Research Innovation Project - Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration 2022kqhm008
6 · The paper itself

Abstract

This study aimed to evaluate the effectiveness of a new combined treatment approach using arthrocentesis, hyaluronic acid (HA) injection, mandibular manipulation (MM), and the Twin-Block appliance (TBA) for managing acute anterior disc displacement without reduction (ADDwoR). A retrospective cross-sectional study was designed. Thirty-seven patients (38 joints) diagnosed with acute ADDwoR were treated with arthrocentesis plus HA combined with MM and TBA in turn from January 2022 to December 2023. The maximum mouth opening (MMO), visual analogue scale (VAS) pain score, condyle/disc position were measured and comparatively analyzed at baseline and one week, three and six months post-treatment. Analysis of variance, Dunnett's T3 analysis, and paired samples t-tests were conducted for statistical analyses setting the threshold for statistical significance at P < 0.05. This treatment achieved a success rate of 94.59% (35/37). After one week of treatment, the MMO exhibited a statistically significant improvement, while the VAS pain scores showed a statistically significant decrease (P < 0.001). Magnetic resonance imaging revealed that at six months post-treatment, there was a significant forward shift in the condylar position compared with pre-treatment (P < 0.001),alongside a significant backward movement of the disc on the affected side (P < 0.001).The combination of arthrocentesis plus HA, MM, and TBA can effectively relieve clinical symptoms and restore the disc-condylar relationship in patients with acute ADDwoR.

Indexed as

ArthrocentesisJoint DislocationsTemporomandibular JointTemporomandibular Joint DiscTemporomandibular Joint DisordersAdultCombined Modality TherapyCross-Sectional StudiesFemaleHumansHyaluronic AcidMagnetic Resonance ImagingMaleMiddle AgedPain MeasurementRetrospective StudiesHyaluronic AcidAnterior disc displacement without reductionMandibular manipulationTemporomandibular jointTwin-block

Identifiers

PMID39905185
PMCPMC11794947

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.