ArticleScientific reports2025
Halodule uninervis extract facilitates the green synthesis of gold nanoparticles with anticancer activity.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Sustainable gold nanoparticles using Jania rubens, targeted therapeutic potential in prostate cancer and mechanistic insights via GO/KEGG pathway analysis.Scientific reports · 2026Article
- Fucoidan-Mediated Biogenic Gold Nanoparticles fromPharmaceuticals (Basel, Switzerland) · 2026Article
- Biogenic Cu-Fe bimetallic nanoparticles induce apoptosis and inhibit invasion in glioblastoma cells.Molecular biology reports · 2026Article
- Eco-friendly synthesis of gold nanoparticles using Gracilaria gracilis with antioxidant potential and biocompatibility.Scientific reports · 2026Article
- Biogenic Synthesis of Gold Nanoparticles UsingNanomaterials (Basel, Switzerland) · 2025Article
- Green Synthesis of Gold Nanoparticles UsingPharmaceuticals (Basel, Switzerland) · 2025Article
- Is 'Green' Gold and Silver Nanoparticle Synthesis Environmentally Friendly?Nanomaterials (Basel, Switzerland) · 2025Review
- Green Synthesis, Characterization, and Potential Antibacterial and Anticancer Applications of Gold Nanoparticles: Current Status and Future Prospects.Biomedicines · 2025Review
- Effect of Green Synthesized FePlants (Basel, Switzerland) · 2025Article
- Biogenic gold nanoparticles synthesized fromOpen life sciences · 2025Article
- Plant metabolites and functional foods in metastatic breast cancer: a supportive strategy for management.Frontiers in pharmacology · 2025Review
- Harnessing marine plant extracts for sustainable agriculture, livestock management, industrial use, and biomedical applications.Frontiers in plant science · 2025Review
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Authors and funding
7 authors.
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Abstract
Gold nanoparticles (AuNPs) have been utilized in a plethora of applications due to their unique optical properties, high stability, and great biocompatibility. The use of plant extracts in the biosynthesis of AuNPs has emerged as an eco-friendly, inexpensive, and nontoxic approach. In the present study, the ethanolic extract of Halodule uninervis (HUE) was used for the first time in the green synthesis of AuNPs. The biogenic AuNPs were characterized using several spectroscopic and microscopic techniques and their anticancer potential was investigated. They displayed a surface plasmon resonance (SPR) band at 550 nm. Scanning electron microscopy (SEM) and Dynamic light scattering (DLS) analysis proved the synthesis of small and spherical AuNPs with a zeta potential of - 27.66 mV. X-ray diffraction (XRD) pattern established the crystalline nature of AuNPs. Thermogravimetric analysis (TGA) and Fourier transform infra-red spectroscopy (FTIR) data confirmed the role of HUE in the capping and stabilization of the manufactured AuNPs. The produced AuNPs exhibited anticancer activity against several human cancer cell lines, highlighting their potential efficacy as anticancer therapeutic agents. Further analysis revealed that this observed cytotoxicity is mediated via the induction of apoptosis. Overall, our data validate the effective use of H. uninervis extract in the biosynthesis of AuNPs with significant biological properties.
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