ArticleScientific reports2025
Socio-demographic disparities in global trends of lip and oral cavity neoplasms from 1990 to 2021.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Biofluid based biochemical and clinicopathological profiling for the detection and stratification of oral potentially malignant disorders.Clinical oral investigations · 2026Article
- Radiotherapy in Squamous Cell Carcinoma of the Lip: A Systematic Review of Reported Practices, Clinical Outcomes, and Gaps in Consensus.Journal of clinical medicine · 2026Review
- Incidence of Malignant Oral Cavity Tumors in the Republic of Serbia: Trend Analysis (1999-2020) and Projections to 2040.Medicina (Kaunas, Lithuania) · 2026Article
- Hemidesmosomal Proteins in Oral Cancer Progression: An Immunohistochemical Study of Human and Mouse.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2026Article
- Burden, Trends and Projection of Lip and Oral Cavity Cancer in Central, Eastern and Western Europe: From the Global Burden of Disease 2023 Study.International dental journal · 2026Article
- Clinical Applications and Diagnostic Performance of Adjunctive Light-Based Optical Technologies in Oral Potentially Malignant Disorders and Squamous Cell Carcinoma: A Systematic Review.Journal of clinical medicine · 2026Review
- Increasing incidence, prevalence, and mortality of lip and oral cavity cancer in adults aged 70 and older globally: findings from GBD 2021.World journal of surgical oncology · 2025Article
- Sociodemographic determinants and assessment of anti-α-Gal IgG titers in head and neck cancer patients.Frontiers in oncology · 2025Article
- Immunohistochemical Markers in the Early Identification of Oral Squamous Cell Carcinoma: A Systematic Review.Clinical, cosmetic and investigational dentistry · 2025Review
- Intratumoral microbial abundance and load influence the immune microenvironment of oral squamous cell carcinoma.Frontiers in oncology · 2025Article
- Current and future burden trends of lip and oral cavity cancer based on estimated annual percentage change and the Bayesian age-period-cohort model: a study based on the global burden of disease 2021.Frontiers in oncology · 2025Article
- Global impact of dietary risks on cancers: burdens across regions from 1990 to 2021 and the projection to 2035.Frontiers in nutrition · 2025Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral cancer, the 13th most common globally, is primarily squamous cell carcinoma linked to tobacco, alcohol, and HPV. Despite advances in care, it remains a major health concern due to high mortality and its impact on quality of life. This study analyzed socio-demographic disparities in oral cancer burden using data from 1990 to 2021. We analyzed annual incidence, mortality, and DALYs across 204 countries, using age-standardized rates and the Socio-demographic Index (SDI) to assess development-related impacts. Statistical methods included Kruskal-Wallis tests, linear regression, joinpoint regression for trends, and Exponential Smoothing for forecasts (2022-2030), with analyses conducted in STATA and Python, and p < 0.05 as significant. Incidence was highest in high SDI countries, while mortality and DALYs were highest in low and middle SDI countries (p < 0.001). From 1990 to 2021, incidence increased (AAPC: 0.5-1.0%), while mortality (APC: - 0.5%) and DALYs (APC: - 0.6%) declined in low SDI regions. Significant disparities across SDI categories (p < 0.001) showed incidence rising with socio-demographic development (R
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