Evidence map›Paper›PMID 39904895›Full record

ArticlePediatric nephrology (Berlin, Germany)2025

Oral health status in children with chronic kidney disease, kidney transplantation, and nephrotic syndrome: a cross-sectional study.

Anna Beyer, Fabian Ebach, Heiko Reutter, Katja Sauerstein, Alina Christine Hilger, Tobias Krickau, Anja Tzschoppe, Joachim Woelfe, Matthias Galiano, Jan Thomas Schaefer

Abstract read
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anna BeyerFriedrich-Alexander Erlangen-Universität, Schloßplatz 4, 91054, Erlangen, Germany. anna-beyer@hotmail.com.
Fabian EbachDepartment of Neonatology and Pediatric Intensive, Care University Hospital Bonn, Bonn, Germany.
Heiko ReutterDepartment of Pediatrics and Adolescent Medicine, Division of Neonatology and Pediatric Intensive Care, University Hospital Erlangen, Erlangen, Germany.
Katja SauersteinDepartment of Pediatrics and Adolescent Medicine, Department of Pediatric Nephrology, University Hospital Erlangen, Erlangen, Germany.
Alina Christine HilgerDepartment of Pediatrics and Adolescent Medicine, Department of Pediatric Nephrology, University Hospital Erlangen, Erlangen, Germany.
Tobias KrickauDepartment of Pediatrics and Adolescent Medicine, Department of Pediatric Nephrology, University Hospital Erlangen, Erlangen, Germany.
Anja TzschoppeDepartment of Pediatrics and Adolescent Medicine, Department of Pediatric Nephrology, University Hospital Erlangen, Erlangen, Germany.
Joachim WoelfeDepartment of Pediatrics and Adolescent Medicine, Department of Pediatric Nephrology, University Hospital Erlangen, Erlangen, Germany.
Matthias GalianoDepartment of Pediatrics and Adolescent Medicine, Department of Pediatric Nephrology, University Hospital Erlangen, Erlangen, Germany.
Jan Thomas SchaeferDepartment of Pediatrics and Adolescent Medicine, Department of Pediatric Nephrology, University Hospital Erlangen, Erlangen, Germany.

Funding

Projekt DEAL
6 · The paper itself

Abstract

introductionChronic kidney disease (CKD) has been previously associated with a decline in oral health. This study aimed to examine the oral health of children with CKD, nephrotic syndrome (NS), and children that received kidney transplantation (KTR).

methodsA case-control study was conducted involving children with CKD stages 1-3, children with CKD stages 4-5, pediatric kidney transplant recipients, and children with NS. Developmental Defects of Enamel (DDE) were evaluated using the DDE Index, while dental caries was assessed with the Decayed Missing Filled Teeth Index (DMFT). Plaque and debris were measured utilizing the Simplified Oral Hygiene Index (OHI-S), which includes the two subindices Simplified Calculus Index (CI-S) and Simplified Debris Index (DI-S).

resultsChildren with CKD 1-3, CKD 4-5, and KTR presented with significantly higher DI-S and CI-S scores and significantly more DDE. There was no difference in the DMFT score in children with CKD 4-5 and KTR. For children with CKD 1-3, a significantly lower DMFT score was observed compared to the control group. Children with NS did not show any differences for DI-S, CI-S, DMFT, and DDE compared to healthy peers.

conclusionOral health status is not affected in children with NS. Children with CKD 1-3, CKD 4-5, and KTR have more plaque, debris, and DDE and should be surveyed regularly by their dentists.

Indexed as

Dental CariesKidney TransplantationNephrotic SyndromeOral HealthRenal Insufficiency, ChronicAdolescentCase-Control StudiesChildChild, PreschoolCross-Sectional StudiesDMF IndexFemaleHumansMaleOral Hygiene IndexChronic kidney diseaseDDEDMFTKidney transplant recipientsNephrotic syndromeOHI-S

Identifiers

PMID39904895
PMCPMC12117002

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.