Evidence map›Paper›PMID 39904821›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025

Associations among positive child health measures in the environmental influences on child health outcomes (ECHO) cohort.

Genevieve L Taylor, Mohamad Burjak, Debashree Ray, Courtney K Blackwell, Hudson P Santos, Jody Ganiban, Anne L Dunlop, Amy J Elliott, Judy L Aschner, Annemarie Stroustrup and 18 more

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Genevieve L TaylorDepartment of Pediatrics, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. gtaylor@med.unc.edu.ORCID http://orcid.org/0000-0002-7192-7976
Mohamad BurjakDepartment of Epidemiology, School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Debashree RayDepartment of Epidemiology, School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Courtney K BlackwellDepartment of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID https://orcid.org/0000-0003-0934-0207
Hudson P SantosSchool of Nursing and Health Studies, University of Miami, Coral Gables, FL, USA.
Jody GanibanDepartment of Psychological & Brain Sciences, The George Washington University, Washington, DC, USA.
Anne L DunlopDepartment of Gynecology & Obstetrics, Emory University School of Medicine, Atlanta, GA, USA.
Amy J ElliottAvera Research Institute, Sioux Falls, SD, USA.
Judy L AschnerHackensack Meridian School of Medicine, Nutley, NJ, USA.
Annemarie StroustrupDivision of Neonatology, Northwell Health, Cohen Children's Medical Center, New Hyde Park, NY, USA.
Traci A BekelmanColorado School of Public Health, Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, Aurora, CO, USA.
Charles BaroneHenry Ford Health + Michigan State University Health Sciences, Detroit, MI, USA.
Carlos A CamargoDepartment of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Cindy T McEvoyPapé Pediatric Research Institute, Oregon Health & Science University, Portland, OR, USA.
Irene TungDepartment of Psychology, California State University Dominguez Hills, Carson, CA, USA.
Julie B SchweitzerDepartment of Psychiatry and Behavioral Sciences, MIND Institute University of California, Davis, Sacramento, CA, USA.
Julie HerbstmanColumbia University Mailman School of Public Health, New York, NY, USA.
Robert O WrightDepartment of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Rosalind J WrightDepartment of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Aderonke A AkinkugbeDepartment of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Rachel S KellyChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Tina V HartertDepartments of Medicine and Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Barron L PattersonDepartments of Medicine and Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Casper BendixsenNational Farm Medicine Center, Marshfield Clinic Research Institute, Marshfield, WI, USA.
Andrea E Cassidy-BushrowHenry Ford Health + Michigan State University Health Sciences, Detroit, MI, USA.
T Michael O'SheaDepartment of Pediatrics, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Rebecca C FryDepartment of Pediatrics, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
program collaborators for Environmental influences on Child Health Outcomes

Funding

Project-005U2COD023375 · OD · DUKE UNIVERSITY · PI Phillip Brian Smith · 2016 to 2026
$215.9M
ECHODAC (Environmental Influences on Child Health Outcomes Data Analysis Center)U24OD023382 · OD · JOHNS HOPKINS UNIVERSITY · PI Diane J Catellier, LISA P JACOBSON · 2016 to 2026
$148.4M
Wisconsin Infant Study Cohort (WISC) ECHO Pediatric Follow-UpUH3OD023282 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI James E. Gern · 2018 to 2026
$64.8M
The NYU Children’s Health & Environment Study: an ECHO CohortUH3OD023305 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Akhgar Ghassabian, Leonardo Trasande · 2018 to 2026
$59.5M
Mount Sinai ECHO site for Perinatal Environment and Development StudiesUH3OD023337 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2018 to 2026
$54.1M
Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
The ECHO Measurement Core: A Framework and Resource for Assessing Environmental Exposure and Child HealthU24OD023319 · OD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Courtney K Blackwell, RICHARD GERSHON · 2016 to 2026
$43.7M
Prenatal and Early Childhood Pathways To Health:  An Integrated Model of Chemical and Social Exposures, Biological Mechanisms, and Sex-Specific Effects on Neurodevelopment and Respiratory OutcomesUH3OD023271 · OD · UNIVERSITY OF WASHINGTON · PI BUSH, NICOLE RENEE, KARR, CATHERINE J · 2018 to 2022
$37.3M
Understanding Breastfeeding Practices Among ECHO Cohort Participants Before and During/After the COVID-19 PandemicUH3OD023285 · OD · MICHIGAN STATE UNIVERSITY · PI Charles James Barone, MICHAEL R. ELLIOTT · 2018 to 2026
$24.5M
Revisiting ReCHARGE: ECHO Follow up on Middle Childhood and AdolescenceUH3OD023365 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Deborah Hall Bennett, Irva Hertz-Picciotto · 2018 to 2026
$21.9M
The Role of the Placenta-Brain Axis in Children's NeurodevelopmentUH3OD023348 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Rebecca Fry, Michael O'SHEA · 2018 to 2026
$21.9M
The Developing Brain: Influences and OutcomesUH3OD023313 · OD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI Viren Andrew D'Sa, Daphne Koinis Mitchell · 2018 to 2026
$20.7M
NCATS NIH HHS UL1 TR004419NHLBI NIH HHS R01 HL159701NIAID NIH HHS U24 AI179612NIH HHS U24 OD023319NIH HHS U24 OD023382NIH HHS U2C OD023375NIH HHS UG3 OD023365NIH HHS UG3 OD035516NIH HHS UG3 OD035517NIH HHS UH3 OD023244NIH HHS UH3 OD023248NIH HHS UH3 OD023253NIH HHS UH3 OD023268NIH HHS UH3 OD023271NIH HHS UH3 OD023272NIH HHS UH3 OD023282NIH HHS UH3 OD023285NIH HHS UH3 OD023288NIH HHS UH3 OD023290NIH HHS UH3 OD023305NIH HHS UH3 OD023313NIH HHS UH3 OD023318NIH HHS UH3 OD023320NIH HHS UH3 OD023328NIH HHS UH3 OD023337NIH HHS UH3 OD023342NIH HHS UH3 OD023347NIH HHS UH3 OD023348NIH HHS UH3 OD023365NIH HHS UH3 OD023389NIH HHS UH3 OD035516NIH Office of the Director U24OD023319NIH Office of the Director U24OD023382NIH Office of the Director U2COD023375NIH Office of the Director UH3OD023244NIH Office of the Director UH3OD023248NIH Office of the Director UH3OD023253NIH Office of the Director UH3OD023268NIH Office of the Director UH3OD02327NIH Office of the Director UH3OD023271NIH Office of the Director UH3OD023282NIH Office of the Director UH3OD023285NIH Office of the Director UH3OD023290NIH Office of the Director UH3OD023305NIH Office of the Director UH3OD023313NIH Office of the Director UH3OD023318NIH Office of the Director UH3OD023320NIH Office of the Director UH3OD023328NIH Office of the Director UH3OD023337NIH Office of the Director UH3OD023342NIH Office of the Director UH3OD023347NIH Office of the Director UH3OD023348NIH Office of the Director UH3OD023365NIH Office of the Director UH3OD023389
6 · The paper itself

Abstract

purposeEffective measurement of positive child health is critical in improving public health. A proposed measure of positive health, a positive child health index (PCHI), is based on how many of 11 specific physical, developmental, and mental health conditions a child has (ranging from 0 to 11). Accepted measures of positive health, Patient-Reported Outcome Measurement Information System (PROMIS®) measures of global health, meaning and purpose, and life satisfaction, are based on child and caregiver perceptions.

methodsThe sample comprised 3713 children aged 5 to 17 years from the NIH Environmental influences on Child Health Outcomes (ECHO) Cohort with data to calculate PCHI and at least 1 child- or caregiver-reported PROMIS measure. Linear regressions were performed to test the associations between each PROMIS measure T-score and the PCHI, adjusting for gestational age, child sex, child age, and maternal factors (age, education, income).

resultsThe PROMIS measure associated most strongly with PCHI was caregiver-reported global health, followed by child-reported global health. Caregiver-reported life satisfaction and child-reported meaning and purpose were higher for children with a PCHI = 0 compared with children with 3 or more health conditions but not when compared with children with only 1 or 2 conditions. Among children with 4 or more conditions, girls reported lower global health than boys. Sex differences were not found for caregiver-reported measures.

conclusionPROMIS measures and PCHI offer complementary information on positive child health. PROMIS measures are intended as measures of a person's perception of their health, whereas PCHI reflects a cumulative impact of chronic health conditions from the perspective of health care systems. Both viewpoints are informative in public health promotion.

Indexed as

Child HealthHealth StatusPatient Reported Outcome MeasuresQuality of LifeAdolescentCaregiversChildChild, PreschoolCohort StudiesFemaleHumansMaleSurveys and QuestionnairesUnited StatesChildHealth statusPatient-reported outcomesPersonal satisfactionResilience (psychological)

Identifiers

PMID39904821
PMCPMC12096410

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.