ArticleOccupational and environmental medicine2025
Occupational risk factors for thumb carpometacarpal joint osteoarthritis: a register-based study of construction workers.
Article in Occupational and environmental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesThe study investigated the association between occupational biomechanical risk factors and the occurrence of thumb carpometacarpal joint osteoarthritis (CMC1 OA) in construction workers.
methodsMale construction workers (n=237 525), participating in a Swedish occupational surveillance programme between 1971 and 1993, were followed between 1997 and 2019. CMC1 OA diagnoses were identified through linkage with national medical registries. Job title, smoking status, height, weight and age were collected from the surveillance programme. A job exposure matrix (JEM) was developed with exposure estimates on biomechanical risk factors for each occupational group. Relative risk (RR) of CMC1 OA diagnosis was calculated using a Poisson regression model.
resultsThere was an increased risk of CMC1 OA for all biomechanical risk factors (RR range 1.3-1.5). Exposure-response patterns were seen for repetitive wrist flexion and extension (low: RR 1.30 (95% CI 1.07 to 1.59), moderate: 1.32 (95% CI 1.07 to 1.62), high: 1.45 (95% CI 1.19 to 1.75)), wrist extension (low: 1.31 (95% CI 1.09 to 1.59), moderate: 1.41 (95% CI 1.17 to 1.70) and heavy lifting (low: 1.13 (95% CI 0.92 to 1.38), moderate: 1.45 (95% CI 1.18 to 1.77), high: 1.50 (95% CI 1.24 to 1.82). Electricians (1.29 (95% CI 1.03 to 1.89)), concrete workers (1.31 (95% CI 1.02 to 1.67)), plumbers (1.37 (95% CI 1.07 to 1.76)), sheet-metal workers (1.58 (95% CI 1.18 to 2.10)), wood workers (1.66 (95% CI 1.36 to 2.03)), repairers (1.75 (95% CI 1.06 to 2.90)) and glass workers (2.21 (95% CI 1.42 to 3.44) had an increased risk of CMC1 OA compared with the reference group.
conclusionWrist movements and hand loading were associated with CMC1 OA.
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