Evidence map›Paper›PMID 39904607›Full record

ArticleMedical physics2025

Electron beam monitoring of a modified conventional medical accelerator with a portable current transformer system traceable to primary electrical standards.

James Renaud, Bryan Richard Muir, Andrew Williams, Malcolm McEwen

Abstract read
In one paragraph

Article in Medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

James RenaudMetrology Research Centre, National Research Council Canada, Ottawa, Ontario, Canada.
Bryan Richard MuirMetrology Research Centre, National Research Council Canada, Ottawa, Ontario, Canada.
Andrew WilliamsWellington Blood and Cancer Centre, Medical Physics, Wellington, New Zealand.
Malcolm McEwenMetrology Research Centre, National Research Council Canada, Ottawa, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUltra-high dose rate radiotherapy (UHDR) delivers therapeutic doses at rates >40 Gy/s in a fraction of a second, aiming to enhance the therapeutic ratio through the FLASH effect. The substantial increase in UHDR beam current poses serious challenges for conventional active dosimeters. Integrating current transformers (ICT) offer a nondestructive solution for accurate monitoring, enabling the type of fast transient readout that will be crucial for UHDR treatment verification. PURPOSE: The aim of this study is to build and characterize a clinically deployable ICT system and to develop an accurate calibration methodology for absolute charge determination that is traceable to primary electrical standards.

methodsThe ICT was constructed from a Super MuMetal

resultsThe ICT responses for nominal test pulses, generated by a function generator and a current pulser, exhibited accurate reproduction of rise and fall times within the 1 ns sampling frequency. A systematic droop effect of 0.6(1)%/µs was observed but is accounted for through the calibration chain. The calibration of the current pulser exhibited a repeatability typically better than 0.05%, with a slowly-varying leakage that can be subtracted using a linear regression of the leakage current. The ICT charge calibration demonstrated a repeatability in the range of (0.5 to < 0.05)% for charge per pulse values in the range of (0.5 to 50) nC, respectively. The ICT response showed a strong linear relationship (adj-R

conclusionsThis work demonstrates the feasibility of accurately calibrating the ICT in terms of absolute charge and applying it as a clinically deployable monitoring system of mA-scale electron beams delivered by a medical accelerator.

Indexed as

ElectronsParticle AcceleratorsRadiometryCalibrationRadiotherapy Dosagebeam current monitorcalorimetrycurrent transformerFLASHUHDR

Identifiers

PMID39904607
PMCPMC11972034

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.