Evidence map›Paper›PMID 39904555›Full record

Observational studyOpen heart2025

Cardiac events and procedures following COVID-19 compared with other pneumonias: a national register study.

Tarjei Øvrebotten, Birgitte Tholin, Kristian Berge, Peder Langeland Myhre, Knut Stavem

Abstract readComparative StudyObservational StudyComparative Study
In one paragraph

Observational study in Open heart, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tarjei ØvrebottenDepartment of Cardiology, Division of Medicine, Akershus University Hospital, Lørenskog, Norway tarjeiovrebotten@gmail.com.ORCID http://orcid.org/0000-0002-5335-7754
Birgitte TholinUniversity of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0001-6768-541X
Kristian BergeDepartment of Cardiology, Division of Medicine, Akershus University Hospital, Lørenskog, Norway.ORCID http://orcid.org/0000-0002-4494-376X
Peder Langeland MyhreDepartment of Cardiology, Division of Medicine, Akershus University Hospital, Lørenskog, Norway.ORCID http://orcid.org/0000-0002-5871-1804
Knut StavemUniversity of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0003-4512-8000

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies have shown an increased risk of cardiac disease following COVID-19, but how it compares to pneumonia of other etiologies is unclear.

aimsTo determine the incidence and HRs of cardiac disease in patients hospitalised with COVID-19 compared with other viral or bacterial pneumonias.

methodsUsing nationwide registry data, we estimated the incidence of cardiac events after hospitalisation with COVID-19 (n=2082) in February to November 2020 vs hospitalisation with viral (n=9018) or bacterial (n=29 339) pneumonia in 2018-2019. We defined outcomes using ICD-10 codes for incident myocarditis, acute myocardial infarction, atrial fibrillation/flutter, heart failure, ischaemic heart disease, other cardiac disease and total cardiac disease (any heart condition). We used Cox regression and logistic regression for analysis.

resultsPatients with COVID-19 had a mean (SD) age of 60 (18) years, compared with 69 (19) years for viral and 72 (17) years for bacterial pneumonia. Those with COVID-19 were more often male and had fewer comorbidities and fewer prior hospitalisations. Patients with COVID-19 had a lower hazard of new-onset cardiac disease compared with viral (HR 0.79 [95%CI 0.66 to 0.93]) and bacterial pneumonia (HR 0.66 [95%CI 0.57 to 0.78]), adjusted for age, sex, comorbidity, hospital admission prior year and respiratory support. Results were similar when including recurrent events.

conclusionPatients hospitalised with COVID-19 had a lower hazard of new-onset cardiac disease during the first 9 months after hospitalisation compared with patients with other viral or bacterial pneumonias after adjusting for multiple possible confounders. However, there may still be residual confounding from other or unknown factors.

Indexed as

COVID-19Heart DiseasesPneumoniaAdultAgedAged, 80 and overFemaleHospitalizationHumansIncidenceMaleMiddle AgedNorwayPneumonia, BacterialPneumonia, ViralRegistriesArrhythmias, CardiacCOVID-19EchocardiographyHeart Failure

Identifiers

PMID39904555
PMCPMC11795400

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.