ArticleBMJ paediatrics open2025
ESPGHAN and NASPGHAN 2024 protocol for paediatric functional constipation treatment guidelines (standard operating procedure).
Article in BMJ paediatrics open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Osmotic and stimulant laxatives for the management of childhood constipation.The Cochrane database of systematic reviews · 2026Pooled it
- European Society for Paediatric Gastroenterology, Hepatology and Nutrition/North American Society for Pediatric Gastroenterology, Hepatology and Nutrition guidelines for treatment of functional constipation in children aged 0-18 years.Journal of pediatric gastroenterology and nutrition · 2026Guideline
- Efficacy and safety of non-pharmacological treatments for paediatric functional constipation: a systematic review and meta-analysis.BMJ paediatrics open · 2026Pooled it
- Bowel Management and Standard Urotherapy in Pediatric Bladder and Bowel Dysfunction: A Randomized Clinical Trial.JAMA network open · 2026Trial
- Bowel Management Protocols in Pediatric Chronic Constipation and Complex Colorectal Dysfunction: A Systematic Review of Sennoside Dosing, Evacuation Strategies, and Radiologic Monitoring.Medeniyet medical journal · 2026Article
- Refractory/therapy-resistant/intractable constipation in children.BMJ paediatrics open · 2026Article
- Teaching stool form recognition in primary school: multimedia versus paper-based instruction using the Bristol stool form scale.Frontiers in public health · 2026Article
- Laparoscopic-assisted transanal soave for refractory constipation in children: outcomes and management.BMC pediatrics · 2025Article
- Epidemiology of childhood constipation: a national study of Swedish children from 2006 to 2023.BMC pediatrics · 2025Article
- Do Most Children with Functional Constipation Meet the Commonly Used Clinical Trial Endpoints?Children (Basel, Switzerland) · 2025Article
- Constipation in Children with Cerebral Palsy: Prevalence, Clinical Manifestations, and Polyethylene glycol vs. Lactulose Efficacy.Iranian journal of child neurology · 2025Article
Corrections and comments
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Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionFunctional constipation is common in childhood, with chronicity leading to a significant impact on patients and their families. There is a significant range of therapies available to healthcare professionals for this condition, with many novel or recently studied. There is a need for an update to the joint European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN)/North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) guidelines last released in 2014. We present the prospectively agreed operating procedure and technical review protocol in this manuscript.
methods'Grading of Recommendations Assessment, Development and Evaluation' (GRADE) will be used for all phases of this guideline development. The Guideline Development Group is formed by paediatric gastroenterologists from both the ESPGHAN as well as the NASPGHAN. A prospective exercise will agree on key outcomes, thresholds of magnitude that are significant at small, moderate and large levels. Systematic evidence searches, selection, extraction, appraisal and analysis will be performed following Cochrane guidance and GRADE guidance for objectively agreeing the certainty of findings. Additional use of network meta-analysis will identify areas of broad triangulation in the evidence. Summary of findings tables will be produced and inform evidence to decision frameworks. These will guide GRADE recommendations with voting to reach a consensus.
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