Evidence map›Paper›PMID 39903834›Full record

ArticleUrology practice2025

Renal Function After Partial Nephrectomy: A Comparative Analysis of Warm, Cold, and No Ischemia Methods.

Sandeep Gurram, Jillian Egan, Maria Antony, Michael A Ahdoot, Nitin K Yerram, Amir H Lebastchi, Heather J Chalfin, Patrick T Gomella, Gennady Bratslavsky, Adam R Metwalli and 2 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Urology practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Sandeep GurramUrologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Jillian EganUrologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Maria AntonyUrologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Michael A AhdootUrologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Nitin K YerramUrologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Amir H LebastchiUrologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Heather J ChalfinUrologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Patrick T GomellaUrologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Gennady BratslavskyUrologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Adam R MetwalliUrologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
W Marston LinehanUrologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Mark W BallUrologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.ORCID 0000-0003-1780-2627

Funding

Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

introductionResults from prior studies show contradictory evidence in determining whether utilization of renal ischemia during partial nephrectomies (PN) results in worse renal functional outcomes. Data assessing a large cohort of patients with no ischemia PN are lacking. The purpose of this study was to evaluate whether the use and type of renal ischemia during PN affects renal functional outcomes.

methodsA retrospective review of 742 patients undergoing PN was assessed and split into 4 cohorts: no ischemia (n = 455), cold ischemia (n = 63), warm ischemia time (WIT) ≤ 30 minutes (n = 164), and WIT > 30 minutes (n = 60). Twelve-month relative glomerular filtration rate (GFR) changes and split function were assessed among the cohorts. Univariate and multivariable regression analyses were used to determine predictors of postoperative acute kidney injury and long-term renal functional outcomes.

resultsNo difference in the mean relative decrease in GFR was noted among the 4 cohorts at either the 3-month (8.7% ± 25.5%,

conclusionsIn patients undergoing PN, the use of and type of ischemia affects short-term but not long-term renal functional outcomes. Facility with multiple ischemia techniques may be useful in the management of patients requiring complex PN.

Indexed as

Acute Kidney InjuryCold IschemiaKidneyKidney NeoplasmsNephrectomyPostoperative ComplicationsWarm IschemiaAgedFemaleGlomerular Filtration RateHumansMaleMiddle AgedRetrospective Studiesischemianephron-sparing surgerypartial nephrectomyrenal cell carcinomarenal function

Identifiers

PMID39903834
PMCPMC12018140

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.