Evidence map›Paper›PMID 39903769›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Biomineralized Nanocomposite-Integrated Microneedle Patch for Combined Brachytherapy and Photothermal Therapy in Postoperative Melanoma Recurrence and Infectious Wound Healing.

Peng Liu, Lu Hao, Jessica C Hsu, Ming Zhou, Zhisheng Luo, Ying Peng, Weibo Cai, Shuo Hu

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Peng LiuDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Changsha, Hunan, 410008, China.ORCID https://orcid.org/0000-0002-2497-6062
Lu HaoDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Changsha, Hunan, 410008, China.
Jessica C HsuDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Ming ZhouDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Changsha, Hunan, 410008, China.
Zhisheng LuoDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Changsha, Hunan, 410008, China.
Ying PengXiangya School of Pharmaceutical Sciences, Central South University, Changsha, Hunan, 410013, China.
Weibo CaiDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, WI, 53705, USA.ORCID https://orcid.org/0000-0003-4641-0833
Shuo HuDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Changsha, Hunan, 410008, China.

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
U.W. RADIOLOGICAL SCIENCES TRAINING PROGRAMT32CA009206 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Bryan Patrick Bednarz · 1985 to 2026
$12.1M
China Postdoctoral Science Foundation 2023M733954Key Program of Ministry of Industry and Information Technology of China CEIEC-2022-ZM02-0219National Natural Science Foundation of China 82272045National Natural Science Foundation of China 82404551National Postdoctoral Program for Innovative Talents BX20230432Natural Science Foundation of Hunan Province in China 2023JJ40966NCI NIH HHS P30 CA014520NCI NIH HHS T32 CA009206Science and Technology Innovation Program of Hunan Province 2021RC4056Youth Science Foundation of Xiangya Hospital 2022Q13
6 · The paper itself

Abstract

In the surgical management of malignant melanoma, incomplete tumor resection and large-area cutaneous defects are major contributors to high locoregional recurrence and uncontrolled wound infections, resulting in poor prognosis and prolonged recovery times for patients. Herein, a versatile nanocomposite microneedle patch (referred to as GM-Ag

Indexed as

BrachytherapyMelanomaNanocompositesNeoplasm Recurrence, LocalPhotothermal TherapySkin NeoplasmsWound HealingAnimalsCell Line, TumorCombined Modality TherapyHumansMiceNeedlesbrachytherapyinfectious wound healinglocal hyperthermiamelanomamicroneedle patchpostoperative recurrence

Identifiers

PMID39903769
PMCPMC11948049

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.